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Evaluation of hemodynamic performance of total cavopulmonary connection (TCPC) with porous inserts

机译:多孔插入物对全腔肺连接(TCPC)的血流动力学性能的评估

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Infants born with univentricular heart disease undergo Fontan surgery to establish separate systemic and pulmonary circulations. This surgery results in better blood circulation across a single ventricle that supplies oxygenated blood to the body and passively returns venous blood to the lungs through the total cavopulmonary connection (TCPC). Reducing the pressure drop across the TCPC during Fontan circulation helps in reducing the work load of univentricular heart, and various designs have been proposed for this purpose. The goal of this work is to analyze the effect of placing a porous insert at an appropriate position in the pulmonary artery, on the pressure drop across the TCPC. A 3D computational model of a total TCPC connection provided with a porous insert is developed and solved by finite volume method, under assumptions of steady, laminar, and Newtonian flows. The effects of the porous medium propertiesporosity and permeabilityacross the connection, are analyzed. Compared to the no-porous medium case, TCPC with the porous medium insert exhibits a maximum reduction of 27% in energy loss for the flow range studied. The porous medium used in TCPC connection lowers the energy dissipation by curtailing the flow recirculation zones across the connection. The influences of the diameter of the blood vessel, total cardiac output, and the thickness, permeability, and position of porous media on energy loss are analyzed. The criteria to select the porous medium properties and position for a given Fontan geometry are also determined.
机译:患有单心室心脏病的婴儿接受Fontan手术以建立独立的全身和肺循环。该手术可改善单个心室的血液循环,该心室将氧合的血液供应给身体,并通过总的腔肺连接(TCPC)被动地将静脉血液返回到肺。在Fontan循环中减少TCPC上的压降有助于减少单心室心脏的工作负荷,为此已经提出了各种设计。这项工作的目的是分析将多孔插入物放置在肺​​动脉中适当位置对TCPC压降的影响。在稳定,层流和牛顿流的假设下,通过有限体积法开发并求解了带有多孔插件的总TCPC连接的3D计算模型。分析了整个连接过程中多孔介质特性多孔性和渗透性的影响。与无孔介质情况相比,带有多孔介质插件的TCPC在所研究的流量范围内最大降低了27%的能量损失。 TCPC连接中使用的多孔介质通过减少跨连接的流动再循环区域来降低能耗。分析了血管直径,总心输出量以及多孔介质的厚度,通透性和位置对能量损失的影响。还确定了选择给定Fontan几何形状的多孔介质特性和位置的标准。

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