In vitro cytotoxicity of novel platinum-based drugs and dichloroacetate against lung carcinoid cell lines

摘要

Introduction Chemotherapy for advanced well-differentiated carcinoids is characterised by low response rates and short duration of responses. The present study aimed to assess the in vitro activity of novel platinum-based chemotherapeutic drugs in combination with dichloroacetate (DCA), a sensitiser to apoptosis, against lung carcinoid cell lines.