Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction

Youlan L. Gu; Adriaan A. Voors; Felix Zijlstra; Hans L. Hillege; Joachim Struck; Serge Masson; Tarcisio Vago; Stefan D. Anker; Ad F. M. van den Heuvel; Dirk J. van Veldhuisen; Bart J. G. L. de Smet

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Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction

机译：速肽释放肽与常规生物标志物在急性心肌梗死中的时空释放模式比较

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摘要

Early detection of acute myocardial infarction (AMI) using cardiac biomarkers of myocardial necrosis remains limited since these biomarkers do not rise within the first hours from onset of AMI. We aimed to compare the temporal release pattern of the C-terminal portion of provasopressin (copeptin) with conventional cardiac biomarkers, including creatine kinase isoenzyme (CK-MB), cardiac troponin T (cTnT), and high-sensitivity cTnT (hs-cTnT), in patients with ST-elevation AMI.

机译：使用心肌坏死的心脏生物标记物对急性心肌梗塞（AMI）的早期检测仍然有限，因为这些生物标记物在AMI发作的最初几小时内不会升高。我们旨在比较前列腺素（copeptin）与常规心脏生物标志物（包括肌酸激酶同工酶（CK-MB），心脏肌钙蛋白T（cTnT）和高敏感性cTnT（hs-cTnT）的C末端部分的暂时释放模式），ST段抬高AMI患者。

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来源
《Clinical Research in Cardiology》 |2011年第12期|p.1069-1076|共8页
作者
Youlan L. Gu; Adriaan A. Voors; Felix Zijlstra; Hans L. Hillege; Joachim Struck; Serge Masson; Tarcisio Vago; Stefan D. Anker; Ad F. M. van den Heuvel; Dirk J. van Veldhuisen; Bart J. G. L. de Smet;
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作者单位

Department of Cardiology, Thorax Center, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700 RB, Groningen, The Netherlands;

Department of Cardiology, Thorax Center, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700 RB, Groningen, The Netherlands;

Thorax Center, Erasmus Medical Center, Rotterdam, The Netherlands;

Department of Cardiology, Thorax Center, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700 RB, Groningen, The Netherlands;

Department of Cardiovascular Research, Instituto Mario Negri, Milan, Italy;

Laboratory of Endocrinology, Ospedale Luigi Sacco, Milan, Italy;

Applied Cachexia Research, Department of Cardiology, Charité, Campus Virchow-Klinikum, Berlin, Germany;

Department of Cardiology, Thorax Center, University Medical Center Groningen, Univ;

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正文语种 eng
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关键词
Copeptin; Acute myocardial infarction; Biomarkers; Temporal release pattern; Troponin;

机译：肽素;急性心肌梗死;生物标志物;暂时释放模式;肌钙蛋白;

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专利

1. Temporal Release Pattern of Copeptin and Troponin T in Patients with Suspected Acute Coronary Syndrome and Spontaneous Acute Myocardial Infarction [J] . Slagman Anna, Searle Julia, Mueller Christian, Clinical Chemistry: Journal of the American Association for Clinical Chemists . 2015,第10期

机译：疑似急性冠状动脉综合征和自发性急性心肌梗死患者中Copeptin和Troponin T的时间释放模式
2. Temporal Release Pattern of Copeptin and Troponin T in Patients with Suspected Acute Coronary Syndrome and Spontaneous Acute Myocardial Infarction [J] . Anna Slagman, Christian Müller, Julia Searle, Clinical Chemistry: Journal of the American Association for Clinical Chemists . 2015,第10期

机译：疑似急性冠脉综合征和自发性急性心肌梗死患者中copeptin和肌钙蛋白T的时间释放模式
3. Copeptin as a prognostic biomarker in acute myocardial infarction [J] . Lattuca Benoit, Sy Vuthy, Nguyen Lee S., International Journal of Cardiology . 2019,第期

机译：Copeptin作为急性心肌梗死的预后生物标志物
4. Mathematical Model of the Release of the cTnT and CK-MB cardiac biomarkers in patients with acute myocardial infarction [C] . Anna Procopio, Salvatore De Rosa, Caterina Covello, European Control Conference . 2019

机译：急性心肌梗死患者cTnT和CK-MB心脏生物标志物释放的数学模型
5. Hematologic Biomarkers Predict Severity and Adverse Events in Acute Myocardial Infarction [D] . Hajihossainlou, Behnam 2019

机译：血液生物标志物可预测急性心肌梗死的严重程度和不良事件
6. Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction [O] . Youlan L. Gu, Adriaan A. Voors, Felix Zijlstra, -1

机译：速肽释放肽与常规生物标志物在急性心肌梗死中的时空释放模式比较
7. Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction [O] . Gu, Youlan L., Voors, Adriaan A., Zijlstra, Felix, 2011

机译：速肽释放肽与常规生物标志物在急性心肌梗死中的时空释放模式比较

Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction

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