Review: storke-prone renovascular hypertensive rats

摘要

Conclusions Because the vascular lesions in cerebrum and heart in RHRSP are similar to that in hu- man beings with hypertension, RHRSP can be used in the studies on mechanisms of hypertensive arterioscle- rotic stroke and cardiac lesions and on verifying the ef- fects of different medications to complications of hyper- tension, and the results might be mire reliable than that in animal models without hypertenison. Purpose To summarized the methods for estab- lishment, characteristics of vascular lesions in brain and heart and the application of stroke-prone renovas- cular hypertensive rats (RHRSP).