LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN PATIENTS WITH ANGINA DECUBITUS

摘要

Objective. To investigate the relationship between left ventricular diastolic dysfunction and episodes of angina decubitus. Methods. The study population consisted of three groups. groups Ⅰ (20 controls) had no cardiovascular diseases. Group Ⅱ (20 patients) had coronary artery disease (CAD) without angina decubitus. Group Ⅲ (24 cases with ejection fraction (EF) > 45%) were selected from 26 patients with angina decubitus. Results. Left ventriculography (LVG) showed that left ventricular (LV) first 1/3 filling fraction (1/3FF) was significantly reduced in groups Ⅲ as compared with groups Ⅱ and Ⅰ (P < 0.01). Left ventricular end-diastolic pressure (LVEDP) significantly increased in patients with angina decubitus after LVG as compared with that before LVG (P < 0.01). However, there were no statistically differences in LVEDP, before and after LVG in both groups Ⅱ and Ⅰ. Conclusions. Patients with angina decubitus have abnormalities of LV diastolic filling and decrease in LV compliance.