Determination of specific IgG4 for diagnosis and therapeutic evaluation of cerebral cysticercosis

摘要

Conclusions The determination of specific IgG4 in sera in a practical method for diagnosis and therapeutic evaluation of cerebral cysticercosis. Objective To probe the significance of specific IgG4 in sera of patients with cerebral cysticercosis for Diagnosis and therapeutic evaluation. Methods Specific IgG4 in sera of patients with cerebral cysticercosis was assessed using colloidal gold- Labeled mouse-anti-human IgG4 as probe. The results were compared with the CT image Manifestation. Results The specific IgG4 positive rate in sera of aptients with cerebral cysticercosis was 97.8/100, Whereas sera from patients with other kinds of parasitosis or central nerve system disease and the control Group well all negative, except for a weak cross-reaction of sera from patients with hepatic Echinococoosis.