Bacterial infections in cirrhotic patients with hepatocellular carcinoma

摘要

AIMS To establish the prevalence of bacterial infection in cirrhotic patients with hepatocellular carcinoma(HCC). METHODS All 719 cirrhotic patients with HCC were investigated retrospectively for the prevalence of bacterial infections. RESULTS The incidence of bacterial infection was 15. 4% (111/719). According to Child-Pugh classification, the incidences of bacterial infection in class A, B and C were 2.3%, 8. 0%, and 26.4%, respectively. The bacterial infection increased with the severity of cirrhosis and severe bacterial infections usually occurred in Child-Pugh class B and C patients. CONCLUSIONS The susceptibility of HCC patients to bacterial infection is mainly due to the underlying cirrhosis and not to the HCC itself.