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The Pharmaceutical Biochemistry Group: Where Pharmaceutical Chemistry Meets Biology and Drug Delivery

机译:药物生物化学小组:药物化学与生物学和药物输送相遇的地方

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摘要

Successful drug discovery and development of new therapeutics is a long, expensive multidisciplinary process needing innovation and the integration of smart cutting edge science and technology to overcome the challenges in taking a drug from the bench to the bedside. The research activities of the Pharmaceutical Biochemistry group span the drug discovery and development process, providing an interface that brings together pharmaceutical chemistry, biochemistry, structural biology, computational chemistry and biopharmaceutics. Formulation and drug delivery are brought into play at an earlier stage when facing the perennial challenge of transforming a potent molecule in vitro into a therapeutic agent in vivo. Concomitantly, drug delivery results can be understood at a molecular level. This broad range of interdisciplinary research activities and competences enables us to address key challenges in modern drug discovery and development, provides a powerful collaborative platform for other universities and the pharmaceutical industry and an excellent training platform for pharmacists and pharmaceutical scientists who will later be involved in drug discovery and development.
机译:成功地发现和开发新疗法的药物是一个漫长而昂贵的多学科过程,需要创新以及智能尖端科学技术的集成,以克服将药物从实验台带到床边的挑战。药物生物化学小组的研究活动涵盖了药物发现和开发过程,提供了一个将药物化学,生物化学,结构生物学,计算化学和生物制药结合在一起的接口。当面临将体外将有效分子转化为体内治疗剂的长期挑战时,制剂和药物递送会在更早的阶段发挥作用。伴随地,药物递送结果可以在分子水平上理解。广泛的跨学科研究活动和能力使我们能够应对现代药物发现和开发中的关键挑战,为其他大学和制药行业提供了强大的协作平台,并为以后将参与其中的药剂师和药学科学家提供了出色的培训平台药物发现与开发。

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