A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers

Mengjie Chen; Chusen Huang; Chunsheng He; Weiping Zhu; Yufang Xu; Yunfeng Lu

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A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers

机译：使用葡萄糖氧化酶门控介孔二氧化硅纳米容器的葡萄糖响应控释系统

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A glucose-responsive controlled-release system based on the competitive combination between glucose oxidase, glucosamine and glucose has been described, which exhibits perfect controlled release properties and high selectivity for glucose over other monosaccharides. This paved the way for a new generation of stimuli-responsive delivery systems.

机译：已经描述了基于葡萄糖氧化酶，葡糖胺和葡萄糖之间竞争性结合的葡萄糖响应性控释系统，该系统表现出完美的控释特性和对葡萄糖的选择性高于其他单糖。这为新一代的刺激响应传递系统铺平了道路。

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《Chemical Communications》 |2012年第76期|p.9522-9524|共3页
作者
Mengjie Chen; Chusen Huang; Chunsheng He; Weiping Zhu; Yufang Xu; Yunfeng Lu;
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Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai 200237, China;

Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai 200237, China;

Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai 200237, China;

Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai 200237, China;

Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai 200237, China;

Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, California 90095, USA;

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1. A glucose-responsive controlled release of insulin system based on enzyme multilayers-coated mesoporous silica particlest [J] . Wenru Zhao, Hongti Zhang, Qianjun He, Chemical Communications . 2011,第33期

机译：基于多层酶涂层中孔二氧化硅颗粒的胰岛素系统的葡萄糖响应控释
2. Mesoporous Silica Nanoparticle-Based Double Drug Delivery System for Glucose-Responsive Controlled Release of Insulin and Cyclic AMP [J] . Yannan Zhao, Brian G. Trewyn, Igor I. Slowing, Journal of the American Chemical Society . 2009,第24期

机译：基于介孔二氧化硅纳米颗粒的双重药物递送系统，用于葡萄糖和胰岛素和环AMP的葡萄糖响应性控释
3. Glucose- and pH-Responsive Controlled Release of Cargo from Protein-Gated Carbohydrate-Functionalized Mesoporous Silica Nanocontainers [J] . Shanshan Wu, Xuan Huang, Xuezhong Du Angewandte Chemie . 2013,第21期

机译：葡萄糖和pH响应控制从蛋白质门控的碳水化合物功能化介孔二氧化硅纳米容器中释放货物。
4. The influence of spatial arrangement fashions on the glucose-responsive controlled release behaviors of insulin-incorporated LbL films [C] . Xingyu Chen, Jun Luo, Wei Wu, World biomaterials congress . 2012

机译：空间排列方式对掺入胰岛素的LbL膜葡萄糖响应控释行为的影响
5. Mesoporous silica nanomaterials and magnetic nanoparticles based stimuli-responsive controlled-release delivery systems. [D] . Giri, Supratim. 2008

机译：中孔二氧化硅纳米材料和磁性纳米粒子为基础的刺激响应控释递送系统。
6. Stimuli-responsive controlled-release system using quadruplex DNA-capped silica nanocontainers [O] . Cuie Chen, Fang Pu, Zhenzhen Huang, 2011

机译：使用四重DNA封端的二氧化硅纳米容器的刺激响应控制释放系统
7. Mesoporous Silica Nanoparticle-Based Double Drug Delivery System for Glucose-Responsive Controlled Release of Insulin and Cyclic AMP [O] . Zhao, Yannan, Trewyn, Brian G., Slowing, Igor I., 2009

机译：基于介孔二氧化硅纳米颗粒的双重药物递送系统，用于葡萄糖和胰岛素和环AMP的葡萄糖响应控释

A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers

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