A monomeric photosensitizer for targeted cancer therapy

Ruizheng Liang; Lina Ma; Lele Zhang; Chunyang Li; Wendi Liu; Min Wei; Dan Yan; David G. Evans; Xue Duan

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A monomeric photosensitizer for targeted cancer therapy

机译：用于靶向癌症治疗的单体光敏剂

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摘要

A targeted photosensitizer used in photodynamic therapy (PDT) was fabricated by incorporation of zinc phthalocyanine (ZnPc) and folic acid (FA) into polyvinylpyrrolidone (PVP) micelles, which exhibits excellent anticancer performance revealed by both in vitro studies and in vivo tests.

机译：通过将酞菁锌（ZnPc）和叶酸（FA）掺入聚乙烯吡咯烷酮（PVP）胶束中来制造用于光动力疗法（PDT）的靶向光敏剂，该胶束在体外研究和体内试验中均显示出优异的抗癌性能。

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来源
《Chemical Communications》 |2014年第95期|14983-14986|共4页
作者
Ruizheng Liang; Lina Ma; Lele Zhang; Chunyang Li; Wendi Liu; Min Wei; Dan Yan; David G. Evans; Xue Duan;
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作者单位

State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China;

Military Institute of Chinese Materia Medica, 302th Military Hospital of China, Beijing 100039, P. R. China;

Military Institute of Chinese Materia Medica, 302th Military Hospital of China, Beijing 100039, P. R. China;

State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China;

State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China;

State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China;

Military Institute of Chinese Materia Medica, 302th Military Hospital of China, Beijing 100039, P. R. China;

State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China;

State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China;

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入库时间 2022-08-17 13:16:41

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1. Target-selective degradation of cancer-related proteins by novel photosensitizers for molecular-targeted photodynamic therapy. [J] . Toshima K, Tanimoto S, Tsumura K Cancer science. . 2009,第9期

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3. Vascular targeted photodynamic therapy with palladium-bacteriopheophorbide photosensitizer for recurrent prostate cancer following definitive radiation therapy: assessment of safety and treatment response. [J] . Trachtenberg J, Bogaards A, Weersink RA, The Journal of Urology . 2007,第5期

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4. MOLECULAR ASSEMBLY OF DNA APTAMER AND PHOTOSENSITIZER FOR TARGETING CANCER THERAPY [C] . Wang Jian, Huang Chengzhi, Tan Weihong, Progress on post-genome technologies and modern natural products . 2011

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6. Bacteriophage Bionanowire as a Carrier for Both Cancer-Targeting Peptides and Photosensitizers and its use in Selective Cancer Cell Killing by Photodynamic Therapy [O] . Naveen Gandra, Gopal Abbineni, Xuewei Qu, -1

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7. Polymeric Encapsulation of a Ru(II)-Based Photosensitizer for Folate-Targeted Photodynamic Therapy of Drug Resistant Cancers [O] . Johannes Karges, Mickaël Tharaud, Gilles Gasser 2021

机译：用于耐药癌的叶酸靶向光动力治疗的ru（II）的聚合物包封。抑制癌症的光敏性

A monomeric photosensitizer for targeted cancer therapy

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