Serum sE-selectin levels and carcinoembryonic antigen mRNA-expressing cells in peripheral blood as prognostic factors in colorectal cancer patients

Patrizia Ferroni MD PhD; Mario Roselli MD; Antonella Spila PhD; Roberta DAlessandro PhD; Ilaria Portarena MD; Sabrina Mariotti MD; Raffaele Palmirotta MD PhD; Oreste Buonomo MD; Giuseppe Petrella MD; Fiorella Guadagni MD PhD

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Serum sE-selectin levels and carcinoembryonic antigen mRNA-expressing cells in peripheral blood as prognostic factors in colorectal cancer patients

机译：血清sE-选择蛋白水平和外周血癌胚抗原mRNA表达细胞作为大肠癌患者的预后因素

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AbstractBACKGROUND:This study analyzed the possible prognostic value of presurgical serum soluble (s)E-selectin levels and/or carcinoembryonic antigen (CEA) mRNA positivity in predicting the disease-free survival of colorectal cancer (CRC) patients.

机译：摘要背景：本研究分析了术前血清可溶性E选择素水平和/或癌胚抗原（CEA）mRNA阳性对预测结直肠癌（CRC）患者无病生存的可能的预后价值。

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来源
《Cancer》 |2010年第12期|p.2913-2921|共9页
作者
Patrizia Ferroni MD PhD; Mario Roselli MD; Antonella Spila PhD; Roberta DAlessandro PhD; Ilaria Portarena MD; Sabrina Mariotti MD; Raffaele Palmirotta MD PhD; Oreste Buonomo MD; Giuseppe Petrella MD; Fiorella Guadagni MD PhD;
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作者单位

Department of Laboratory Medicine and Advanced Biotechnologies, Scientific Institute for Research, Hospitalization and Health Care (IRCCS) San Raffaele, Rome, Italy;

|Scientific Institute for Research, Hospitalization and Health Care (IRCCS) San Raffaele, Rome, Italy|Division of Medical Oncology, Department of Internal Medicine, University of Rome “

Tor Vergata,”

Tor Vergata Clinical Center, Rome, Italy;

Department of Laboratory Medicine and Advanced Biotechnologies, Scientific Institute for Research, Hospitalization and Health Care (IRCCS) San Raffaele, Rome, Italy;

Department of Laboratory Medicine and Advanced Biotechnologies, Scientific Institute for Research, Hospitalization and Health Care (IRCCS) San Raffaele, Rome, Italy;

Division of Medical Oncology, Department of Internal Medicine, University of Rome “

Tor Vergata,”

Tor Vergata Clinical Center, Rome, Italy;

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正文语种 eng
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关键词
colorectal cancer; blood-borne cells; carcinoembryonic antigen; sE-selectin; metastasis;

机译：大肠癌;血细胞;癌胚抗原;sE-选择素;转移;

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专利

1. Serum sE-selectin levels and carcinoembryonic antigen mRNA-expressing cells in peripheral blood as prognostic factors in colorectal cancer patients. [J] . Ferroni P, Roselli M, Spila A, Cancer: A Journal of the American Cancer Society . 2010,第12期

机译：血清sE-选择蛋白水平和外周血中表达癌胚抗原mRNA的细胞是大肠癌患者的预后因素。
2. Eligibility of antigenic-peptide-pre-loaded and fixed adhesive peripheral blood cells for induction of cytotoxic T lymphocytes from cancer patients with elevated serum levels of carcinoembryonic antigen. [J] . Kim CH, Todoroki T, Matsumura M, Journal of Cancer Research and Clinical Oncology . 2000,第7期

机译：抗原肽预加载的和固定的粘附性外周血细胞有资格从患有癌胚抗原的血清水平升高的癌症患者中诱导细胞毒性T淋巴细胞。
3. Detection of carcinoembryonic antigen messenger RNA-expressing cells in peripheral blood 7 days after curative surgery is a novel prognostic factor in colorectal cancer. [J] . Sadahiro S, Suzuki T, Maeda Y, Annals of surgical oncology . 2007,第3期

机译：根治性手术后7天检测外周血癌胚抗原信使RNA表达细胞是结直肠癌的一种新的预后因素。
4. CLINICAL AND PROGNOSTIC SIGNIFICANCE OF PREOPERATIVE SERUM CA15-3,CEA AND TPS LEVELS IN PATIENTS WITH PRIMARY BREAST CANCER [C] . Yu-hong Zheng, Yan Chen, Ying-ying Lin 2011 Asia-Pacific Conference of tumor biology and medicine . 2011

机译：原发性乳腺癌患者术前血清CA15-3，CEA和TPS水平的临床和预后意义
5. Carcinoembryonic antigen (CEA) inhibits anoikis in colorectal cancer (CRC) cells by interfering with TRAIL-R2 (DR5) signaling [D] . Samara, Raed N. 2006

机译：癌胚抗原（CEA）通过干扰TRAIL-R2（DR5）信号传导来抑制结直肠癌（CRC）细胞的失神经
6. Prognostic and predictive value of serum carcinoembryonic antigen levels in advanced non-small cell lung cancer patients with epidermal growth factor receptor sensitive mutations and receiving tyrosine kinase inhibitors [O] . Xin Min Zhao, Jing Zhao, Kai Lin Xing, 2017

机译：血清癌胚抗原水平对表皮生长因子受体敏感突变并接受酪氨酸激酶抑制剂的晚期非小细胞肺癌患者的预后和预测价值
7. Serum sE-selectin levels and carcinoembryonic antigen mRNA-expressing cells in peripheral blood as prognostic factors in colorectal cancer patients [O] . Ferroni P, Roselli M, Spila A, 2010

机译：血清sE-选择蛋白水平和外周血癌胚抗原mRNA表达细胞作为大肠癌患者的预后因素

Serum sE-selectin levels and carcinoembryonic antigen mRNA-expressing cells in peripheral blood as prognostic factors in colorectal cancer patients

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