Treatment of obesity: need to focus on high risk abdominally obese patients

摘要

A simple measurement such as waist circumference can indicate accumulation of abdominal fat.rnViscerally obese men are characterised by an atherogenic plasma lipoprotein profile.rnA triad of non-traditional markers for coronary heart disease found in viscerally obese middle aged men (hyperinsulinaemia, raised apolipoprotein B concentration, and small LDL particles) increases the risk of coronary heart disease 20-fold.rnFour out of five middle aged men with a waist measurement ≥90 cm and triglyceride concentrations ≥2 mmol/l are characterised by this triad.rnEven in the absence of hypercholesterolaemia, hyperglycaemia, or hypertension, obese patients could be at high risk of coronary heart disease if they have this "hypertriglyceridaemic waist" phenotype.