Obstructive sleep apnea event prediction using recurrence plots and convolutional neural networks (RP-CNNs) from polysomnographic signals

摘要

The prediction of Obstructive Sleep Apnea (OSA) through common polysomnographic signals before stop breathing triggers the ventilation-aided machines such as Continuous Positive Airway Pressure (CPAP). In this paper, a novel schema is proposed based on the representation of the dynamical behavior of polysomnographic signals. This procedure is accomplished using a combination of the Recurrence Plots (RPs) and Convolutional Neural Networks (CNNs), called RP-CNNs. In this regard, the OSA events of 30, 60, 90, and 120 s are predicted before the occurrence. The first phase was to create RP images via Electroencephalogram (EEG), Electrocardiogram (ECG), and respiration signals at a single level. Then, the RP images were independently fed into two fast and robust pre-trained CNNs, naming ResNet-18 and ShuffleNet. Thus, the networks were fine-tuned, and the mentioned events were classified. In the second phase, the classification results were fused using the Weighted Majority Voting (WMV) method to make the final decision. Finally, subject-dependent and subject-independent evaluation criteria were utilized for the MIT-BIH polysomnographic and Dublin sleep apnea databases. The RPShuffleNet and 10-fold cross-validation were employed to attain the highest average accuracy and Area Under the Curve (AUC) through 30-second intervals before the OSA events at fusion-level in MIT-BIH polysomnographic and Dublin sleep apnea databases. The achieved results were 90.72%, 0.8937, 90.45%, and 0.9010, respectively. Predicting the OSA events using representation of the dynamical behavior of polysomnographic signals and the fusion of results of the fine-tuned CNNs have been led to the enhancement of the results compared to the state-of-the-art studies.