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首页> 外文期刊>Australasian physical & engineering sciences in medicine >Treatment plan complexity metrics for predicting IMRT pre-treatment quality assurance results
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Treatment plan complexity metrics for predicting IMRT pre-treatment quality assurance results

机译:用于预测IMRT预处理质量保证结果的治疗计划复杂性指标

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摘要

The planning of IMRT treatments requires a compromise between dose conformity (complexity) and deliverability. This study investigates established and novel treatment complexity metrics for 122 IMRT beams from prostate treatment plans. The Treatment and Dose Assessor software was used to extract the necessary data from exported treatment plan files and calculate the metrics. For most of the metrics, there was strong overlap between the calculated values for plans that passed and failed their quality assurance (QA) tests. However, statistically significant variation between plans that passed and failed QA measurements was found for the established modulation index and for a novel metric describing the proportion of small apertures in each beam. The 'small aperture score' provided threshold values which successfully distinguished deliverable treatment plans from plans that did not pass QA, with a low false negative rate.
机译:IMRT治疗的计划要求在剂量一致性(复杂性)和可传递性之间做出折衷。这项研究调查了来自前列腺治疗计划的122条IMRT光束的既定和新颖的治疗复杂性指标。使用“治疗和剂量评估者”软件从导出的治疗计划文件中提取必要的数据并计算指标。对于大多数指标,通过和未通过质量保证(QA)测试的计划的计算值之间存在很大的重叠。但是,对于已建立的调制指数和描述每个光束中小孔径比例的新颖度量,发现通过和未通过QA测量的计划之间存在统计学上的显着差异。 “小孔径得分”提供了阈值,可以成功地将可交付的治疗计划与未​​通过质量检查的计划区分开来,假阴性率低。

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  • 作者单位

    Science and Engineering Faculty, Queensland University of Technology, Brisbane, QLD, Australia;

    Science and Engineering Faculty, Queensland University of Technology, Brisbane, QLD, Australia,Genesis Cancer Care Queensland, Brisbane, QLD, Australia;

    Epworth Radiation Oncology, Melbourne, VIC, Australia;

    Genesis Cancer Care Queensland, Brisbane, QLD, Australia;

    Genesis Cancer Care Queensland, Brisbane, QLD, Australia;

    Science and Engineering Faculty, Queensland University of Technology, Brisbane, QLD, Australia;

    Science and Engineering Faculty, Queensland University of Technology, Brisbane, QLD, Australia;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Quality assurance; Beam complexity; Radiation therapy;

    机译:质量保证;光束复杂度;放射治疗;

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