Development and antibacterial performance of silver nanoparticles-lecithin modified montmorillonite nanoparticle hybrid

摘要

It is advisable to develop novel and more effective biocompatible antimicrobial materials to reduce the threats of bacterial infection. To study this problem, silver nanoparticles (AgNPs) are studied for their excellent performance against bacteria. In this work, montmorillonite (Mt) was modified with lecithin (LEC). Then, silver ion (Ag+) was loaded on the LEC-Mt. Finally, Ag+ was reduced to Ag nanoparticles (AgNPs) by good biocompatible reducing agent ascorbic acid. X-ray diffraction and X-ray photoelectron spectroscopy identified that AgNPs were successfully reduced. Scanning electron microscope and transmission electron microscope proved the presence and formation mechanism of AgNPs. Antimicrobial activity of the AgNPs@ LEC-Mt showed a significant improvement on Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) compared with bare Mt. and LEC modified Mt. The cytotoxicity effects of AgNPs@LEC-Mt were examined in L-929 cells line with a survival rate over 80%.