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Epigenetic potential of resveratrol and analogs in preclinical models ofn prostate cancer

机译:白藜芦醇及其类似物在前列腺癌临床前模型中的表观遗传潜力

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摘要

Lifestyle, particularly diet, is a risk factor for prostate cancer. Dietary polyphenols such as resveratrol possess anticancer properties and therefore have chemopreventive and therapeutic potential. Resveratrol has pleiotropic effects, exerting its biological activity through multiple pathways and targets, including those associated with cancer. Numerous studies have demonstrated the anticancer effects of resveratrol and, to a lesser extent, its analogs, in tissue culture, while in vivo observa
机译:生活方式,特别是饮食,是前列腺癌的危险因素。膳食多酚(如白藜芦醇)具有抗癌特性,因此具有化学预防和治疗的潜力。白藜芦醇具有多效作用,可通过多种途径和靶标(包括与癌症有关的途径)发挥其生物学活性。大量研究表明,白藜芦醇及其类似物在组织培养中的抗癌作用较小,而在体内观察时

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