Stromal Osteonectin Overexpression Is Associated with Poor Outcome in Patients with Ampullary Cancer

Mark Bloomston MD; E. Christopher Ellison MD; Peter Muscarella MD; Osama Al-Saif MBBS; Edward W. Martin MD; W. Scott Melvin MD; Wendy L. Frankel MD

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Stromal Osteonectin Overexpression Is Associated with Poor Outcome in Patients with Ampullary Cancer

机译：壶腹癌患者间质骨连接蛋白过表达与不良结果相关

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摘要

Osteonectin has been suggested to be important in the progression of pancreatic cancer but has not been correlated with survival. We determined the osteonectin expression and its influence on survival in patients with ampullary carcinoma.

机译：骨粘连蛋白被认为在胰腺癌的进展中很重要，但与存活率无关。我们确定了骨连接蛋白的表达及其对壶腹癌患者生存的影响。

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来源
《Annals of Surgical Oncology 》 |2007年第1期| 211-217| 共7页
作者
Mark Bloomston MD; E. Christopher Ellison MD; Peter Muscarella MD; Osama Al-Saif MBBS; Edward W. Martin MD; W. Scott Melvin MD; Wendy L. Frankel MD;
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作者单位

Department of Surgery Ohio State University N924 Doan Hall 410 W. 10th Ave. Columbus OH 43210 USA;

Department of Surgery Ohio State University N924 Doan Hall 410 W. 10th Ave. Columbus OH 43210 USA;

Department of Surgery Ohio State University N924 Doan Hall 410 W. 10th Ave. Columbus OH 43210 USA;

Department of Surgery Ohio State University N924 Doan Hall 410 W. 10th Ave. Columbus OH 43210 USA;

Department of Surgery Ohio State University N924 Doan Hall 410 W. 10th Ave. Columbus OH 43210 USA;

Department of Surgery Ohio State University N924 Doan Hall 410 W. 10th Ave. Columbus OH 43210 USA;

Department of Pathology Ohio State University 129 Hamilton Hall 1645 Neil Ave. Columbus OH 43210 USA;

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原文格式 PDF
正文语种 eng
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关键词
Ampulla of Vater; Ampullary cancer; Osteonectin; Osteopontin; Tissue microarray; Survival;

机译：壶腹;壶腹癌;骨连接蛋白;骨桥蛋白;组织芯片;生存;

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专利

1. Stromal osteonectin overexpression is associated with poor outcome in patients with ampullary cancer. [J] . Bloomston M, Ellison EC, Muscarella P, Annals of surgical oncology . 2007 ,第1期

机译：壶腹癌患者间质骨连接蛋白过度表达与不良预后相关。
2. Re: Outcome of Patients with Micropapillary Urothelial Carcinoma following Radical Cystectomy: ERBB2 (HER2) Amplification Identifies Patients with Poor Outcome Editorial Comment - Re: Significance of ERBB2 Overexpression in Therapeutic Resistance and Cancer-Specific Survival in Muscle-Invasive Bladder Cancer Patients Treated with Chemoradiation-Based Selective Bladder-Sparing Approach Editorial Comment [J] . Chang Sam S. The Journal of Urology . 2015 ,第3期

机译：Re：患有微量膀胱切除术后的患者的结果：ERBB2（HER2）扩增鉴定了较差的结果患者编辑评论 - RE：肌肉侵袭性膀胱癌患者治疗性抗性和癌症特异性存活中的ERBB2过表达的意义基于选择性的膀胱保留方法编辑评论
3. Re: Outcome of Patients with Micropapillary Urothelial Carcinoma following Radical Cystectomy: ERBB2 (HER2) Amplification Identifies Patients with Poor Outcome Editorial Comment - Re: Significance of ERBB2 Overexpression in Therapeutic Resistance and Cancer-Specific Survival in Muscle-Invasive Bladder Cancer Patients Treated with Chemoradiation-Based Selective Bladder-Sparing Approach Editorial Comment [J] . Chang Sam S. The Journal of Urology . 2015 ,第3期

机译：回复：根治性膀胱切除术后微乳头状尿路上皮癌患者的结果：ERBB2（HER2）扩增可确定结果较差的患者基础的选择性膀胱保留方法社论评论
4. Up-Regulation of Enhancer of Zeste Homolog 2 Is Associated Positively With Cyclin Dl Overexpression and Poor Clinical Outcome in Head and Neck Squamous Cell Carcinoma [C] . Wei Cao, Zhien Feng, Zhibin Cui, Academic Committee conference of Shanghai key lab of stomatology . 2011

机译：Zeste同源2的增强子的上调与Cyclin Dl过度表达和头颈部鳞状细胞癌的不良临床结果呈正相关。
5. National and Institutional Outcomes Data in Head and Neck Cancers, and Functional and Patient Reported Outcomes in Patients with Oropharyngeal Cancers. [D] . Kansal, Ankit. 2017

机译：头颈癌的国家和机构结局数据，以及口咽癌患者的功能和患者报告结局。
6. Overexpression of BUB1B contributes to progression of prostate cancer and predicts poor outcome in patients with prostate cancer [O] . Xin Fu, Guo Chen, Zhi-duan Cai, 2016

机译：BUB1B的过表达有助于前列腺癌的进展并预测前列腺癌患者的预后不良
7. Cyclooxygenase-2 overexpresion is associated with a poor outcome in resected ampullary cancer patients. [O] . SANTINI D, VINCENZI B, TONINI G, 2005

机译：在切除的壶腹癌患者中，环氧合酶2的过度表达与不良预后相关。

Stromal Osteonectin Overexpression Is Associated with Poor Outcome in Patients with Ampullary Cancer

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