Feasibility and improvement in production of ~(191)Os/~(191m)Ir generator by Tehran Research Reactor (TRR)

摘要

This manuscript describes an investigation on the production of ~(191)Os/191mIr by Tehran Research Reactor (TRR). ~(191)Os-hexachloro-osmate was obtained by thermal neutron (4 × 1013 cm~(-2) s~(-1)) irradiation of enriched ~(190)0s sample followed by fusion with KOH and KNO_3 in acidic media. One of the important radionuclide impurities is ~(192)Ir that is produced during irradiation in reactor. Separation this impurity from ~(191)Os is developed by a new approach in this research and the total recovery yield of ~(191)Os is about 99% and the total time required for completion the procedure is about 30 min. This method improved the yield and the time of performance in comparison with values published in literature. ~(191)Os is loaded on an anion-exchange column and ~(191m)Ir eluted with normal saline. Each elution is 1 ml of 0.9% saline at pH 6.5-7. The yield of generator was assessed for 2 weeks. ~(191m)Ir yield is 15-18% and ~(191)Os breakthrough is about 2 × 10~(-4)2 × 10~(-3).