Ultrahigh mass accfuracy in isotope-selective collision-induced dissociation using correlated sweep excitation and sustained off-resonance irradiation: A Fourier transform ion cyclotron resonance mass spectrometry case study on the [M+2h]~2+ ion of b

摘要

Using electrospray ionization with a 9.4 T Fourier trans- form mass spectrometer, fragment ion spectra were acquired for a single isotopomer of doubly protonated bradykinin(molecular mass, 1059.6 Da). Correlated sweep excitation methods were applied to mass-select the single isotopomer(m/z=530.8). Sustained off-reso- nance irradiation was used to activate and fragment the ions.