Predicting Peak Symmetry in Capillary Zone Electrophoresis: The Concept of the Peak Shape Diagram

摘要

Electrophoretic peaks generally deviate from the sym- metrical Gaussian shape that is expected when diffusion is the dominant dispersion factor. A basic understanding of the electromigrational dispersion processes which give rise to peak asymmetry shows that these effects are related to the difference in mobilities between the sample ions and the buffer electrolyte ions.