Characterization of Pseudostationary Phases in Micellar Electrokinetic Chromatography by Applying Linear Solvation Energy Relationships and Retention Indexes

摘要

The influence of different solute-micelle interactions on micellar solubilization is studied by using linear solvation energy relationship(LSER) modeling. The LSER results for six anionic micellar systems demonstrate that the migration behavior of neutral species in micellar electro- kinetic chromatography(MEKC) is mainly determined by their molar volume and their hydrogen bond acceptor ability. Their polarity and hydrogen bond donor ability are shown to be of minor importance with these anionic surfactants.