The Effect of Repeated Ozone Exposures on Inflammatory Markers in Bronchoalveolar Lavage Fluid and Mucosal Biopsies

摘要

The aim of this study was to investigate the cellular and biochemi - cal events associated with repeated exposures to ozone. Twenty three healthy subjects underwent single exposures to 200 ppb ozone and to filtered air (FA), as well as repeated exposures to 200 ppb ozone on 4 consecutive days, each for 4 h of intermittent ex - ercise. Bronchoalveolar lavage was performed and mucosal biop - sies were taken 20 h after the single or the last of the repeated ex - posures.