Sensitization to cat allergen is associated with asthma in older men and predicts new-onset airway hyperresponsiveness

摘要

To explore the relationship between sensitization to inhalant allergens and adult asthma, we per- formed two nested case-control studies of men being followed in the VA Normative Aging Study. In Study A, 46 subjects (mean age, 61.2±8.1 yr) with symptoms of asthma and an abnormal methacho- Line challenge test (cases) were compared with 92 age- and smoking-history-matched subjects, who Denied symptoms and had normal methacholine challenge tests (controls).