Population distributions of allele frequency of apolipoprotein E by age and gender in Han Chinese

摘要

AIM: To study apolipoproteins E (ApoE) allele frequency in Han Chinese based on age and gender from Shanghai metropolitan area. METHODS: Healthy Han Chinese people (F: 237 and M: 412) were involved in this study. ApoE gene was amplified by PCR using the Forward primer: 5'-GGC ACG GCT GTC CAA GGA GCT-3' and reverse primer: 5'-GAT GGC GCT GAG GCC GCG CT-3'. CONCLUSION: The frequen- Cies of Apo*2, ApoE*3, and ApoE*4 were Demonstrated in the normal Chinese population.