Persistent right ventricular dysfunction increased risk for recurrent venous thromboembolism after acute pulmonary embolism

摘要

In patients who present with submassive (hemodynamically stable) PE,n2 in 5 will have RVD, typically defined by RV hypokinesis (1). Althoughnthis finding has been associated with increased short-term mortality, thenuse of more aggressive thrombolytic therapy does not reduce mortalitynor recurrent VTE more than does conventional anticoagulation (2).nFurthermore, RVD is transient in about half of affected patients. Thus,nthe long-term significance of RVD in patients with acute PE remainsnunclear.