No cardiac testing for intermediate-risk patients on β-blockers was noninferior to testing before vascular surgery for preventing death and nonfatal MI

摘要

Cardiac death and nonfatal MI are common and serious events in thenperioperative period, with rates up to 30% in high-risk patients (thosenwith ≥ 3 risk factors based on the Revised Cardiac Risk Index [RCRI])nhaving vascular surgery (1). Observational studies (2) and some randomizedntrials (3) suggest that perioperative β-blocker therapy providesnmyocardial protection in intermediate-risk (RCRI score 1 to 2) andnhigh-risk (RCRI score ≥ 3) patients.