Bio‐absorbable sealants for reinforcing the pancreatic stump after distal pancreatectomy are critical

摘要

BackgroundBio‐absorbable sealants are widely used to reduce the rate and severity of postoperative pancreatic fistulas after distal pancreatectomy. However, numerous clinical trials have failed to demonstrate their clinical benefit. We therefore investigated stability and bio‐compatibility of absorbable sealants in vitro and in vivo.