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A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial

机译：INP研究：热休克蛋白70 / glypican-3衍生的多种HLA结合肽以及hLAG-3Ig和Poly-ICLC的新型联合佐剂用于转移性胃肠道癌患者：YNP01试验

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The online version of this article (10.1007/s00262-020-02518-7) contains supplementary material, which is available to authorized users.

机译：本文的在线版本（10.1007 / s00262-020-02518-7）包含补充材料，可供授权用户使用。

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期刊名称 Springer Open Choice
作者
Masao Nakajima; Shoichi Hazama; Koji Tamada; Keiko Udaka; Yasunobu Kouki; Toshinari Uematsu; Hideki Arima; Akira Saito; Shun Doi; Hiroto Matsui; Yoshitaro Shindo; Satoshi Matsukuma; Shinsuke Kanekiyo; Yukio Tokumitsu; Shinobu Tomochika; Michihisa Iida; Shin Yoshida; Yuki Nakagami; Nobuaki Suzuki; Shigeru Takeda; Shigeru Yamamoto; Shigefumi Yoshino; Tomio Ueno; Hiroaki Nagano;
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作者单位

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年(卷),期 -1(69),8
年度 -1
页码 -1
总页数 12
原文格式 PDF
正文语种
中图分类外科学;
关键词
Peptide vaccination therapy; Multi-HLA binding; HLAG-3Ig plus Poly-ICLC; Gastrointestinal cancers;

机译：肽疫苗治疗;多重HLA结合;HLAG-3Ig加Poly-ICLC;胃肠道癌;

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专利

1. A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial [J] . Nakajima Masao, Hazama Shoichi, Tamada Koji, Cancer immunology, immunotherapy : . 2020,第8期

机译：衍生自热休克蛋白70 /甘锡-3的多HLA结合肽的I阶段研究，以及用于转移胃肠癌患者的HLAG-3IG和Poly-ICLC的新型组合佐剂：YNP01试验
2. Heat Shock Protein 70 (Hsp70) Peptide Activated Natural Killer (NK) Cells for the Treatment of Patients with Non-Small Cell Lung Cancer (NSCLC) after Radiochemotherapy (RCTx) – From Preclinical Studies to a Clinical Phase II Trial [J] . Hanno M. Specht, Norbert Ahrens, Christiane Blankenstein, Frontiers in Immunology . 2015,第12期

机译：热休克蛋白70（Hsp70）肽激活的自然杀伤（NK）细胞用于放射化学治疗（RCTx）后的非小细胞肺癌（NSCLC）患者的治疗-从临床前研究到临床II期试验
3. Heat Shock Protein 70 (Hsp70) Peptide Activated Natural Killer (NK) Cells for the Treatment of Patients with Non-Small Cell Lung Cancer (NSCLC) after Radiochemotherapy (RCTx) – From Preclinical Studies to a Clinical Phase II Trial [J] . Hanno M. Specht, Norbert Ahrens, Christiane Blankenstein, Frontiers in Immunology . 2015,第4期

机译：热休克蛋白70（Hsp70）肽激活的自然杀伤（NK）细胞用于放射化学治疗（RCTx）后的非小细胞肺癌（NSCLC）患者的治疗-从临床前研究到临床II期试验
4. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
5. Heat Shock Protein 70 (Hsp70) Peptide Activated Natural Killer (NK) Cells for the Treatment of Patients with Non-Small Cell Lung Cancer (NSCLC) after Radiochemotherapy (RCTx) – From Preclinical Studies to a Clinical Phase II Trial [O] . Hanno M. Specht, Norbert Ahrens, Christiane Blankenstein, 2015

机译：热休克蛋白70（Hsp70）肽激活的自然杀伤（NK）细胞用于放射化学治疗（RCTx）后的非小细胞肺癌（NSCLC）患者的治疗-从临床前研究到临床II期试验
6. A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial [O] . Masao Nakajima, Shoichi Hazama, Koji Tamada, 2020

机译：阶段I研究来自热休克蛋白70 /甘锡-3的多HLA结合肽，以及用于转移胃肠癌患者的HLAG-3IG和Poly-ICLC的新型组合佐剂：YNP01试验

A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial

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