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Treatment outcome of supraglottoplasty vs. wait-and-see policy in patients with laryngomalacia

机译:喉软化症患者的声门上成形术治疗结果与静观观

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摘要

In most cases, laryngomalacia presents as a mild disease, and the symptoms resolve after wait-and-see policy. Up to 20 % of patients present with severe laryngomalacia and may require surgery (i.e. supraglottoplasty); however, the indication for surgery is not firmly established yet. The goal of this study is to determine whether supraglottoplasty results in a better outcome than wait-and-see and to investigate how different comorbidities influence outcome. A retrospective study of pediatric cases of in a tertiary referral center was performed. Photo and video documentation was available and revised in all cases. Electronic and paper charts were reviewed for the following variables: gender, sex, gestational age, birth weight, symptoms, comorbidity, date of endoscopy, severity and type of laryngomalacia, treatment modality and technique and follow-up data and a total 89 patients were included. Supraglottoplasty was found to lead to significantly faster complete improvement of laryngomalacia than wait-and-see policy (5 weeks vs. 29, p = 0.026). Synchronous airway lesions (SALs) were present in 40.4 % of patients and were associated with prolonged symptoms of laryngomalacia (38.5 weeks vs. 14.5, p = 0.043). Supraglottoplasty is safe and effective in treatment of severe laryngomalacia. SALs and comorbidities are frequently found in patients with laryngomalacia and are responsible for longer onset of complaints.Electronic supplementary materialThe online version of this article (doi:10.1007/s00405-016-3943-3) contains supplementary material, which is available to authorized users.
机译:在大多数情况下,喉软化症是一种轻度疾病,在采取观望政策后症状可缓解。多达20%的患者患有严重的喉软化症,可能需要手术(即声门上膜成形术);然而,手术的指征尚不明确。这项研究的目的是确定眼睑成形术是否比等待观望的结果更好,并调查不同合并症如何影响结果。对三级转诊中心的儿科病例进行了回顾性研究。提供了照片和视频文档,并在所有情况下都进行了修订。电子和纸质图表检查了以下变量:性别,性别,胎龄,出生体重,症状,合并症,内窥镜检查日期,喉软化的严重程度和类型,治疗方式和技术以及随访数据,共有89例患者包括在内。发现泪膜上皮成形术比完全静观治疗能显着更快地完全缓解喉头软化(5周vs.29,p = 0.026)。同步气道病变(SAL)在40.4%的患者中存在,并伴有喉头软化症的长期症状(38.5周vs.14.5,p = 0.043)。睑上整形术治疗严重的喉头软化症是安全有效的。 SAL和合并症在喉头软化症患者中经常出现,并导致更长时间的投诉。电子补充材料本文的在线版本(doi:10.1007 / s00405-016-3943-3)包含补充材料,授权用户可以使用。

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