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Thyroid Stimulating Hormone Receptor (TSHR) Intron 1 Variants Are Major Risk Factors for Graves Disease in Three European Caucasian Cohorts

机译：甲状腺刺激激素受体（TSHR）内含子1变异是三个欧洲白种人队列中格雷夫斯氏病的主要危险因素

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BackgroundThe thyroid stimulating hormone receptor (TSHR) gene is an established susceptibility locus for Graves' disease (GD), with recent studies refining association to two single nucleotide polymorphisms (SNPs), rs179247 and rs12101255, within TSHR intron 1.

机译：背景甲状腺刺激激素受体（TSHR）基因是Graves病（GD）的既定易感基因座，最近的研究精炼与TSHR内含子1中的两个单核苷酸多态性（SNP）rs179247和rs12101255的关联。

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期刊名称 PLoS Clinical Trials
作者
Rafał Płoski; Oliver J. Brand; Beata Jurecka-Lubieniecka; Maria Franaszczyk; Dorota Kula; Paweł Krajewski; Muhammad A. Karamat; Matthew J. Simmonds; Jayne A. Franklyn; Stephen C. L. Gough; Barbara Jarząb; Tomasz Bednarczuk;
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年(卷),期 2010(5),11
年度 2010
页码 e15512
总页数 6
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专利

1. Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease. [J] . Brand OJ, Barrett JC, Simmonds M Human Molecular Genetics . 2009,第9期

机译：甲状腺刺激激素受体基因（TSHR）与Graves病的关联。
2. Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves’ disease [J] . Oliver J. Brand1 Jeffrey C. Barrett2 Matthew J. Simmonds1 Paul R. Newby1 Christopher J. McCabe1 Christopher K. Bruce1 Boris Kysela1 Jackie D. Carr-Smith1 Thomas Brix4 Penny J. Hunt1 Wilmar M. Wiersinga5 Laszlo Hegedüs4 John Connell6 John A.H. Wass3 Jayne A. Franklyn1 Anthony P. Weetman7 Joanne M. Heward1 and Stephen C.L. Gough1* Human Molecular Genetics . 2009,第9期

机译：甲状腺刺激激素受体基因（TSHR）与格雷夫斯病的关系
3. Immunization of mice with a newly identified thyroid-stimulating hormone receptor splice variant induces Graves'-like disease [J] . EndoT., KobayashiT. Journal of Autoimmunity . 2013,第Null期

机译：用新鉴定的促甲状腺激素受体剪接变体对小鼠进行免疫接种会引起Graves样疾病
4. Association of Exon 10A and 10B inactivating mutation of follicle stimulating hormone receptor gene (FSHR) and Polycystic Ovarian Syndrome in Vellore cohort [C] . NishuSekar, Rucha Kulkarni, SharvariOzalkar International Conference on Science, Engineering the Technology . 2018

机译：外显子10A和10B脱膜刺激激素受体基因（FSHR）和卵巢卵巢综合征在Vellore Cohort中的突变结合
5. Initial characterization of the thyroid stimulating hormone receptor knock-out mouse: The TSH receptor...it's not just for thyroids anymore. [D] . Marians, Russell Craig. 2002

机译：甲状腺刺激激素受体基因敲除小鼠的初步特征：TSH受体……不再仅限于甲状腺。
6. Genetic associations of the thyroid stimulating hormone receptor gene with Graves diseases and Graves ophthalmopathy: A meta-analysis [O] . Haibo Xiong, Mingxing Wu, Hong Yi, -1

机译：甲状腺刺激激素受体基因与Graves病和Graves眼病的遗传关联：荟萃分析
7. Thyroid stimulating hormone receptor (TSHR) intron 1 variants are major risk factors for Graves' disease in three European Caucasian cohorts. [O] . Płoski, R, Brand, OJ, Jurecka-Lubieniecka, B, 2010

机译：甲状腺刺激激素受体（TSHR）内含子1变异是三个欧洲白种人队列中Graves病的主要危险因素。
8. Epidermal Growth Factor (EGF) Receptor Intron 1 CA Repeat Polymorphisms in African-American and Caucasian Males: Influence on Prostate Cancer Risk or Disease Progression and Interaction with Androgen Receptor CAG Repeat Polymorphisms [R] . Moscatello, D. K. 2005

机译：表皮生长因子（EGF）受体内含子1 Ca在非洲裔美国人和高加索人男性中重复多态性：对前列腺癌风险或疾病进展的影响以及与雄激素受体CaG重复多态性的相互作用

Thyroid Stimulating Hormone Receptor (TSHR) Intron 1 Variants Are Major Risk Factors for Graves Disease in Three European Caucasian Cohorts

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