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Mitotic Arrest and Apoptosis in Breast Cancer Cells Induced by Origanum majorana Extract: Upregulation of TNF-α and Downregulation of Survivin and Mutant p53

机译：牛至提取物诱导乳腺癌细胞的有丝分裂阻滞和凋亡：TNF-α的上调与Survivin和突变型p53的下调

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BackgroundIn the present study, we investigated the effect of Origanum majorana ethanolic extract on the survival of the highly proliferative and invasive triple-negative p53 mutant breast cancer cell line MDA-MB-231.

机译：背景在本研究中，我们研究了牛至的乙醇提取物对高度增殖和侵袭性三阴性p53突变型乳腺癌细胞MDA-MB-231存活的影响。

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期刊名称 PLoS Clinical Trials
作者
Yusra Al Dhaheri; Ali Eid; Synan AbuQamar; Samir Attoub; Mohammad Khasawneh; Ghenima Aiche; Soleiman Hisaindee; Rabah Iratni;
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年(卷),期 2010(8),2
年度 2010
页码 e56649
总页数 14
原文格式 PDF
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专利

1. Blockade of Rac1 activity induces G1 cell cycle arrest or apoptosis in breast cancer cells through downregulation of cyclin D1, survivin, and X-linked inhibitor of apoptosis protein. [J] . Yoshida T, Zhang Y, Rivera Rosado LA, Molecular cancer therapeutics . 2010,第6期

机译：Rac1活性的阻断通过下调细胞周期蛋白D1，survivin和X连锁的凋亡蛋白抑制剂诱导乳腺癌细胞G1周期停滞或凋亡。
2. The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. [J] . Gao J, Morgan WA, Sanchez Medina A, Toxicology and Applied Pharmacology . 2011,第3期

机译：黄cut的乙醇提取物和活性化合物诱导人肺癌细胞的细胞周期停滞和凋亡，包括上调p53和Bax。
3. Nordamnacanthal induced apoptosis and mitotic-G2/M arrest with downregulation of Bcl-2 in the human breast cancer cell line (MCF-7) [J] . Norsyafini Ishak, Latifah Saiful Yazan, Nordin Haji Lajis Medical and Health Science Journal . 2010,第7期

机译：Nordamnacanthal诱导人乳腺癌细胞系（MCF-7）中Bcl-2的下调并诱导凋亡和有丝分裂G2 / M阻滞
4. Curcuma zanthorrhiza Extracts Induce G2/M Cell Cycle Arrest and Apoptosis in 4T1 and MCF-7 Human Breast Cancer Cells [C] . Sari Haryanti, Galuh Ratnawati, Nuning Rahmawati International Symposium on Health Research;National Congress of The Indonesian Public Health Association . 2020

机译：Curcuma Zanthorrhiza提取物在4T1和MCF-7人乳腺癌细胞中诱导G2 / M细胞循环骤停和细胞凋亡
5. RS-41, A multi-targeted kinase inhibitor, induces cell cycle arrest and apoptosis in P53 mutant and wild type models of upper gastrointestinal cancers. [D] . Visal, Tanvi. 2017

机译：RS-41是一种多靶点激酶抑制剂，在上消化道癌的P53突变型和野生型模型中诱导细胞周期停滞和凋亡。
6. Anticancer pyridines induce G2/M arrest and apoptosis via p53 and JNK upregulation in liver and breast cancer cells [O] . Vasilis P. Androutsopoulos, Demetrios A. Spandidos -1

机译：抗癌吡啶通过肝癌和乳腺癌细胞中的p53和JNK上调诱导G2 / M阻滞和凋亡
7. Mitotic Arrest and Apoptosis in Breast Cancer Cells Induced by Origanum majorana Extract: Upregulation of TNF-α and Downregulation of Survivin and Mutant p53 [O] . Al Dhaheri, Yusra, Eid, Ali, AbuQamar, Synan, 2013

机译：牛至提取物诱导乳腺癌细胞的有丝分裂阻滞和凋亡：TNF-α的上调与Survivin和突变型p53的下调
8. Susceptibility to Radiation Induced Apoptosis and Senescence in p53 Wild Type and p53 Mutant Breast Tumor Cells [R] . DeMasters, G. 2006

机译：p53野生型和p53突变乳腺癌细胞辐射诱导细胞凋亡和衰老的易感性

Mitotic Arrest and Apoptosis in Breast Cancer Cells Induced by Origanum majorana Extract: Upregulation of TNF-α and Downregulation of Survivin and Mutant p53

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