Treatment of CoQ10 Deficient Fibroblasts with Ubiquinone CoQ Analogs and Vitamin C: Time- and Compound-Dependent Effects

摘要

BackgroundCoenzyme Q10 (CoQ10) and its analogs are used therapeutically by virtue of their functions as electron carriers, antioxidant compounds, or both. However, published studies suggest that different ubiquinone analogs may produce divergent effects on oxidative phosphorylation and oxidative stress.