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DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats

机译：Ped鱼鲨偶然胆碱能神经元的Dreadd活化逆转电机缺陷并在帕金森大鼠中恢复纹状体多巴胺信号传导

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The online version of this article (10.1007/s13311-019-00830-4) contains supplementary material, which is available to authorized users.

机译：本文的在线版本（10.1007 / s13311-019-00830-4）包含补充材料，可供授权用户使用。

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期刊名称 NeuroRx
作者
Puneet K. Sharma; Lisa Wells; Gaia Rizzo; Joanna L. Elson; Jan Passchier; Eugenii A. Rabiner; Roger N. Gunn; David T. Dexter; Ilse S. Pienaar;
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作者单位

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年(卷),期 2020(17),3
年度 2020
页码 1120–1141
总页数 22
原文格式 PDF
正文语种
中图分类神经科学;
关键词
Cholinergic; dopamine; DREADD; motor behavior; pedunculopontine nucleus; positron emission tomography.;

机译：胆碱能量;多巴胺;Dreadd;运动行为;Pedinculopontine核;正电子发射断层扫描。;

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专利

1. DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats [J] . Puneet K. Sharma, Lisa Wells, Gaia Rizzo, Neurotherapeutics . 2020,第3期

机译：Ped鱼鲨偶然胆碱能神经元的Dreadd活化逆转电机缺陷并在帕金森大鼠中恢复纹状体多巴胺信号传导
2. Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson’s disease [J] . Ilse S. Pienaar, Sarah E. Gartside, Puneet Sharma, Molecular neurodegeneration . 2015,第S1期

机译：在帕金森氏病大鼠模型中，胆碱能足小神经元神经元的药物遗传学刺激可逆转运动功能障碍
3. Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno‐Free Conditions Restore Motor Deficits in Parkinsonian Rodents [J] . Jonathan C. Niclis, Carlos W. Gantner, Walaa F. Alsanie, Stem cells translational medicine. . 2017,第3期

机译：在无异种条件下，来自人多能干细胞的有效指定的腹中脑多巴胺神经元可恢复帕金森病鼠的运动障碍。
4. A hybrid platform based on EOG and EEG signals to restore communication for patients afflicted with progressive motor neuron diseases [C] . A. B. Usakli, S. Gurkan, F. Aloise, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2009

机译：一种基于Eog和EEG信号的混合平台，以恢复患者患有渐进式电机神经元疾病的患者的沟通
5. Cholinergic regulation of corticostriatal signaling in striatal medium spiny neurons and cellular adaptation following dopamine depletion. [D] . Ding, Jun. 2007

机译：多巴胺耗竭后纹状体中棘神经元的皮质口神经通路信号通路的胆碱能调节和细胞适应。
6. Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson’s disease [O] . Ilse S. Pienaar, Sarah E. Gartside, Puneet Sharma, 2015

机译：在帕金森氏病大鼠模型中胆碱能足小神经元神经元的药物遗传学刺激可逆转运动功能障碍
7. DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats [O] . Puneet K. Sharma, Lisa Wells, Gaia Rizzo, 2020

机译：Ped鱼鲨偶然胆碱能神经元的Dreadd活化逆转电机缺陷并在帕金森大鼠中恢复纹状体多巴胺信号传导
8. Alterations in Muscarinic Control of Striatal Dopamine Autoreceptors in Senescence: A Deficit at the Ligand-Muscarinic Receptor Interface [R] . Joseph, J. A., Dalton, T. K., Roth, G. S., 1988

机译：纹状体多巴胺自身受体的衰弱控制在衰老中的变化：配体 - 毒蕈碱受体界面的缺陷

DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats

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