Evidence for CD16a-Mediated NK Cell Stimulation in Antibody-Mediated Kidney Transplant Rejection

机译：抗体介导的肾脏移植排斥反应中CD16a介导的NK细胞刺激的证据。

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Natural killer (NK) cells localize in the microcirculation in antibody-mediated rejection (AMR) and have been postulated to be activated by donor-specific anti-HLA antibodies triggering their CD16a Fc receptors. However, direct evidence for NK cell CD16a triggering in AMR is lacking. We hypothesized that CD16a-inducible NK cell-selective transcripts would be expressed in human AMR biopsies and would offer evidence for CD16a triggering.

机译：天然杀伤（NK）细胞位于抗体介导的排斥（AMR）中的微循环中，并已被推测可被触发其CD16a Fc受体的供体特异性抗HLA抗体激活。但是，缺乏在AMR中触发NK细胞CD16a的直接证据。我们假设CD16a诱导的NK细胞选择性转录本将在人的AMR活检中表达，并为CD16a触发提供证据。

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期刊名称 Lippincott Williams Wilkins Open Access
作者
Michael D. Parkes; Philip F. Halloran; Luis G. Hidalgo;
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年(卷),期 -1(101),4
年度 -1
页码 -1
总页数 10
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1. Evidence for CD16a-Mediated NK Cell Stimulation in Antibody-Mediated Kidney Transplant Rejection [J] . Parkes Michael D., Halloran Philip F., Hidalgo Luis G. Transplantation: Official Journal of the Transplantation Society . 2017,第4期

机译：CD16A介导的NK细胞刺激在抗体介导的肾移植排斥反应中的证据
2. NK cell transcripts and NK cells in kidney biopsies from patients with donor-specific antibodies: evidence for NK cell involvement in antibody-mediated rejection. [J] . Hidalgo LG, Sis B, Sellares J, American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons . 2010,第8期

机译：来自供体特异性抗体患者肾脏活检中的NK细胞转录物和NK细胞：NK细胞参与抗体介导的排斥反应的证据。
3. NK Cell Transcripts and NK Cells in Kidney Biopsies from Patients with Donor-Specific Antibodies: Evidence for NK Cell Involvement in Antibody-Mediated Rejection [J] . L. G. Hidalgo, B. Sis, J. Sellares, American Journal of Transplantation . 2010,第8期

机译：供体特异性抗体患者肾脏活检中的NK细胞转录本和NK细胞：NK细胞参与抗体介导的排斥反应的证据
4. An optimised ensemble for antibody-mediated rejection status prediction in kidney transplant patients [C] . Mariel Barbachan e Silva, Pilib Ó Broin IEEE Congress on Evolutionary Computation . 2020

机译：用于肾脏移植患者抗体介导排斥状态预测的优化组合
5. Circulating B Cells with Memory and Antibody-Secreting Phenotypes Are Detectable in Pediatric Kidney Transplant Recipients Before the Development of Antibody-Mediated Rejection [D] . Fischman, Clara. 2019

机译：在发育抗体介导的排斥之前，在儿科肾移植受者中可检测到具有记忆和抗体分泌表型的循环B细胞
6. Efficacy and Safety of Bone Marrow-Derived Mesenchymal Stem Cells for Chronic Antibody-Mediated Rejection After Kidney Transplantation- A Single-Arm Two-Dosing-Regimen Phase I/II Study [O] . Yongcheng Wei, Xiaoyong Chen, Huanxi Zhang, 2021

机译：肾移植后慢性抗体介导的慢性抗体介导的排斥反应的骨髓间充质干细胞的疗效和安全性 - 单臂双剂量 - 方案I / II期研究
7. Pure T-cell-mediated rejection following kidney transplant according to the response to treatment in the era of antibody-mediated rejection [O] . Hyunwook Kwon, Sung Shin, Duck Jong Han, 2020

机译：纯T细胞介导的肾移植后排斥反应根据抗体介导的抑制时代治疗的反应

Evidence for CD16a-Mediated NK Cell Stimulation in Antibody-Mediated Kidney Transplant Rejection

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