Cells exhibit transient nuclear envelope ruptures during interphase, but the responsible biophysical processes remain unclear. In this issue, Hatch and Hetzer (2016. J. Cell Biol. ) show that actin fibers constrict the nucleus, causing chromatin protrusions and nuclear membrane ruptures at sites with nuclear lamina defects.
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机译：细胞在相间期表现出短暂的核膜破裂，但负责的生物物理过程仍不清楚。在这个问题上，Hatch和Hetzer（2016. J. Cell Biol。）表明肌动蛋白纤维会收缩核，导致染色质突起和核膜破裂处的核膜破裂。
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