Study of altered functional connectivity in individuals at risk for Alzheimer’s Disease

摘要

BACKGROUND: Mild Cognitive Impairment (MCI) has been considered to have a high risk in converting into Alzheimer’s Disease (AD). Previous studies showed that AD was associated with changes in resting-state networks (RSNs). However, few studies have evaluated the altered functional connectivity in early mild cognitive impairment (EMCI) and late mild cognitive impairment (LMCI).