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De-implementation of inappropriately tight control (of hypoglycemia) for health: protocol with an example of a research grant application

机译:取消对健康的不适当的严格控制(低血糖):带有研究资助申请示例的方案

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摘要

BackgroundImplementation of practice change is difficult and large scale implementation is particularly difficult. Among the challenges facing the healthcare system in general and healthcare organizations is the overuse of low value care. Improving medication safety also constitutes an attempt to reduce low value or potentially harmful care. Critical issues of overuse of low value practices and medication safety intersect in overtreatment of diabetes. Specifically, (over)intensive glycemic control increases hypoglycemia risk and morbidity without providing meaningful benefit. Our work indicates that among patients with diabetes who are at high risk for hypoglycemia, potential overtreatment is common. The Choosing Wisely Initiative to reduce low value care led by the American Board of Internal Medicine Foundation recommends not to treat most persons over 65 years of age with medications to reduce the A1c<7.5%. For most physicians this involves a change in practice. We will study the implementation of the Veterans Health Administration's Choosing Wisely Initiative (which includes hypoglycemic safety as a targeted condition) with three specific aims: (1) to assess the overall impact, both intended and unintended, of the Choosing Wisely Initiative to reduce overtreatment of diabetes in especially vulnerable populations; (2) to assess the impact of commitment to quality, teaching intensity, and safety culture on likelihood of overtreatment; and (3) to identify configurations of the implementation strategy, provider characteristics and organizational level factors that are associated with successful reduction of overtreatment rates by comparing high and low performers. Because focus on this initiative could have the unintended consequence of paying less attention to poor glycemic control (A1c>9%), we will also assess undertreatment.
机译:背景技术难以实施实践改变,并且大规模实施特别困难。普通医疗机构和医疗机构所面临的挑战之一是过度使用低价值医疗。改善药物安全性也构成了减少低价值或潜在有害护理的尝试。过度使用低价值做法和药物安全性等关键问题与糖尿病的过度治疗有关。具体而言,过度(过度)的血糖控制会增加低血糖症的风险和发病率,而不会提供有意义的益处。我们的工作表明,在患有低血糖高风险的糖尿病患者中,潜在的过度治疗很普遍。由美国内科医学基金会领导的明智选择减少低价值护理的倡议建议不要对大多数65岁以上的人进行药物治疗以降低A1c <7.5%。对于大多数医生而言,这涉及实践的改变。我们将研究退伍军人卫生管理局的“明智选择倡议”(包括降低血糖的安全性作为目标条件)的实施,其三个具体目标:(1)评估“明智选择倡议”的总体影响,包括有意和无意的,以减少过度治疗在特别脆弱的人群中患糖尿病; (2)评估对质量,教学强度和安全文化的承诺对过度治疗可能性的影响; (3)通过比较高绩效者和低绩效者,确定与成功降低过度治疗率相关的实施策略的配置,提供者特征和组织水平因素。因为专注于此计划可能会产生意想不到的后果,即减少对血糖控制不佳的关注(A1c> 9%),因此我们还将评估治疗不足。

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