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Prevalence of COPD and Tobacco Smoking in Tunisia — Results from the BOLD Study

机译:突尼斯的COPD流行和吸烟—大胆研究的结果

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摘要

In Tunisia, there is a paucity of population-based data on Chronic Obstructive Pulmonary Disease (COPD) prevalence. To address this problem, we estimated the prevalence of COPD following the Burden of Lung Disease Initiative. We surveyed 807 adults aged 40+ years and have collected information on respiratory history and symptoms, risk factors for COPD and quality of life. Post-bronchodilator spirometry was performed and COPD and its stages were defined according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. Six hundred and sixty one (661) subjects were included in the final analysis. The prevalence of GOLD Stage I and II or higher COPD were 7.8% and 4.2%, respectively (Lower Limit of Normal modified stage I and II or higher COPD prevalence were 5.3% and 3.8%, respectively). COPD was more common in subjects aged 70+ years and in those with a BMI < 20 kg/m2. Prevalence of stage I+ COPD was 2.3% in <10 pack years smoked and 16.1% in 20+ pack years smoked. Only 3.5% of participants reported doctor-diagnosed COPD. In this Tunisian population, the prevalence of COPD is higher than reported before and higher than self-reported doctor-diagnosed COPD. In subjects with COPD, age is a much more powerful predictor of lung function than smoking.
机译:在突尼斯,很少有基于人口的慢性阻塞性肺疾病(COPD)患病率数据。为了解决这个问题,我们根据《肺病负担倡议》估算了COPD的患病率。我们调查了807位40岁以上的成年人,并收集了有关呼吸史和症状,COPD危险因素和生活质量的信息。根据全球慢性阻塞性肺疾病倡议(GOLD)指南进行了支气管扩张剂后肺活量测定,并确定了COPD及其阶段。六百一十一(661)名受试者被纳入最终分析。 GOLD I期和II期或更高的COPD患病率分别为7.8%和4.2%(正常改良I期和II期或更高COPD的患病率下限分别为5.3%和3.8%)。 COPD在70岁以上的受试者和BMI <20 kg / m 2 的受试者中更为常见。在少于10包年的吸烟中,I + COPD阶段的患病率为2.3%,而超过20包年的吸烟率为16.1%。只有3.5%的参与者报告了医生诊断的COPD。在此突尼斯人口中,COPD的患病率高于以前报告的水平,也高于自我报告的医生诊断的COPD。在患有COPD的受试者中,年龄是比吸烟更有效地预测肺功能的指标。

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