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Nanomedicines in the Management of Alzheimer’s Disease: Current View and Future Prospects

机译:纳米药物在阿尔茨海默病管理中的应用:现状与展望

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摘要

Alzheimer’s disease (AD) is a kind of dementia that creates serious challenges for sufferers’ memory, thinking, and behavior. It commonly targeting the aging population and decay the brain cells, despite attempts have been performed to enhance AD diagnostic and therapeutic techniques. Hence, AD remains incurable owing to its complex and multifactorial consequences and still there is lack of appropriate diagnostics/therapeutics option for this severe brain disorder. Therefore, nanotechnology is currently bringing new tools and insights to improve the previous knowledge of AD and ultimately may provide a novel treatment option and a ray of hope to AD patients. Here in this review, we highlighted the nanotechnologies-based findings for AD, in both diagnostic and therapeutic aspects and explained how advances in the field of nanotechnology/nanomedicine could enhance patient prognosis and quality of life. It is highly expected these emerging technologies could bring a research-based revolution in the field of neurodegenerative disorders and may assist their clinical experiments and develop an efficacious drug for AD also. The main aim of review is to showcase readers the recent advances in nanotechnology-based approaches for treatment and diagnosing of AD.
机译:阿尔茨海默病 (AD) 是一种痴呆症,对患者的记忆、思维和行为构成严重挑战。它通常针对老龄化人群并腐蚀脑细胞,尽管已经尝试加强 AD 诊断和治疗技术。因此,由于其复杂和多因素的后果,AD 仍然无法治愈,并且仍然缺乏针对这种严重脑部疾病的适当诊断/治疗选择。因此,纳米技术目前正在带来新的工具和见解,以提高对 AD 的先前知识,并最终可能为 AD 患者提供一种新的治疗选择和希望之光。在这篇综述中,我们强调了基于纳米技术的 AD 诊断和治疗方面的发现,并解释了纳米技术/纳米医学领域的进步如何提高患者的预后和生活质量。人们非常期待这些新兴技术将在神经退行性疾病领域带来一场基于研究的革命,并可能协助他们的临床实验并开发一种有效的 AD 药物。综述的主要目的是向读者展示基于纳米技术的 AD 治疗和诊断方法的最新进展。

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