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Self-assembled peptide nanomaterials for biomedical applications: promises and pitfalls

机译:用于生物医学应用的自组装肽纳米材料:希望与陷阱

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摘要

Over the last several decades, a great number of advances have been made in the area of self-assembled supramolecules for regenerative medicine. Such advances have involved the design, preparation, and characterization of brand new self-assembled peptide nanomaterials for a variety of applications. Among all biomolecules considered for self-assembly applications, peptides have attracted a great deal of attention as building blocks for bottom-up fabrication, due to their versatility, ease of manufacturing, low costs, tunable structures, and versatile properties. Herein, some of the more exciting new designs of self-assembled peptides and their associated unique features are reviewed and several promising applications of how self-assembled peptides are advancing drug delivery, tissue engineering, antibacterial therapy, and biosensor device applications are highlighted.
机译:在过去的几十年中,用于再生医学的自组装超分子领域取得了许多进展。这些进展涉及用于各种应用的全新自组装肽纳米材料的设计,制备和表征。在考虑用于自组装应用的所有生物分子中,由于其多功能性,易于制造,低成本,可调节的结构和多功能特性,肽作为自下而上制造的基础材料已经引起了广泛的关注。本文对自组装肽的一些更令人兴奋的新设计及其相关的独特功能进行了综述,并着重介绍了自组装肽如何促进药物递送,组织工程,抗菌疗法和生物传感器设备应用的一些有前途的应用。

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