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The role of the ERK1/2 pathway in simvastatin-loaded nanomicelles and simvastatin in regulating the osteogenic effect in MG63 cells

机译：ERK1 / 2途径在辛伐他汀负载的纳米胶束和辛伐他汀在调节MG63细胞成骨作用中的作用

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ObjectivesThe present study aimed to clarify the role of the ERK1/2 pathway in simvastatin (SV)-loaded nanomicelles (SVNs)- and SV-mediated promotion of cell osteogenic differentiation and explore the molecular mechanisms by which SVNs exhibited a greater efficacy in promoting osteogenic differentiation than SV.

机译：目的本研究旨在阐明ERK1 / 2途径在辛伐他汀（SV）负载的纳米胶束（SVNs）和SV介导的细胞成骨分化促进中的作用，并探索SVN发挥更大的促进成骨作用的分子机制。分化比SV。

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期刊名称 International Journal of Nanomedicine
作者
Mao Niu; Xianling Feng; Lei Zhou;
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作者单位

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年(卷),期 2018(13),-1
年度 2018
页码 8165–8178
总页数 14
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
simvastatin-loaded nanomicelles ERK1/2 pathway dental implant restoration osteogenic effect;

机译：辛伐他汀负载的纳米胶束;ERK1 / 2途径;牙种植体修复;成骨作用;

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专利

1. The role of the ERK1/2 pathway in simvastatin-loaded nanomicelles and simvastatin in regulating the osteogenic effect in MG63 cells [J] . Mao Niu, Xianling Feng, Lei Zhou International Journal of Nanomedicine . 2018,第3期

机译：ERK1 / 2途径在辛伐他汀负载的纳米胶束和辛伐他汀在调节MG63细胞成骨作用中的作用
2. The roles of extracellular signal-regulated kinase 1/2 pathway in regulating osteogenic differentiation of murine preosteoblasts MC3T3-E1 cells on roughened titanium surfaces. [J] . Zhuang LF, Jiang HH, Qiao SC, Journal of biomedical materials research, Part A . 2012,第1期

机译：细胞外信号调节激酶1/2通路在调节粗糙钛表面上的鼠成骨细胞MC3T3-E1细胞成骨分化中的作用。
3. The roles of extracellular signal-regulated kinase 1/2 pathway in regulating osteogenic differentiation of murine preosteoblasts MC3T3-E1 cells on roughened titanium surfaces. [J] . Zhuang LF, Jiang HH, Qiao SC, Journal of biomedical materials research, Part A . 2012,第1期

机译：细胞外信号调节激酶1/2途径在粗产钛表面上调节鼠的骨质发生分化。
4. Erk1/2 mitogen-activated protein kinase pathway involves in myostatin-regulated differentiation repression [C] . Wei Yang, Yan Chen, Yong Zhang, 中国遗传学会七届二次青年研讨会论文汇编 . 2006

机译：Erk1 / 2丝裂原激活的蛋白激酶途径参与肌生成抑制素调节的分化抑制。
5. Signaling pathway from the A(2B) adenosine receptor to extracellular signal-regulated kinases (ERK1/2) in human umbilical vein endothelial cells (HUVEC) and its role in HUVEC proliferation [D] . Fang, Ying 2006

机译：从A（2B）腺苷受体到人脐静脉内皮细胞（HUVEC）中细胞外信号调节激酶（ERK1 / 2）的信号通路及其在HUVEC增殖中的作用
6. Regulative Effect of Mir-205 on Osteogenic Differentiation of Bone Mesenchymal Stem Cells (BMSCs): Possible Role of SATB2/Runx2 and ERK/MAPK Pathway [O] . Nan Hu, Chunzhen Feng, Yi Jiang, 2015

机译：Mir-205对骨间充质干细胞（BMSCs）成骨分化的调控作用：SATB2 / Runx2和ERK / MAPK途径的可能作用
7. The role of the ERK1/2 pathway in simvastatin-loaded nanomicelles and simvastatin in regulating the osteogenic effect in MG63 cells [O] . Mao Niu, Xianling Feng, Lei Zhou 2018

机译：ERK1 / 2途径在辛伐他汀负载纳米钙和辛伐他汀在调节MG63细胞中的骨质发生效果中的作用

The role of the ERK1/2 pathway in simvastatin-loaded nanomicelles and simvastatin in regulating the osteogenic effect in MG63 cells

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