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Influence of CFH HTRA1 and ARMS2 polymorphisms in the response to intravitreal ranibizumab treatment for wet age-related macular degeneration in a Spanish population

机译：CFHHTRA1和ARMS2多态性对玻璃体腔雷珠单抗治疗湿性年龄相关性黄斑变性的反应的影响

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摘要

AIMTo determine whether gene polymorphisms of the major genetic risk loci for age-related macular degeneration (AMD): ARMS2 (rs10490923), the complement factor H (CFH) (rs1410996) and HTRA1 (rs11200638) influence the response to a treatment regimen with ranibizumab for exudative AMD.

机译：目的确定年龄相关性黄斑变性（AMD）的主要遗传风险基因座的基因多态性：ARMS2（rs10490923），补体因子H（CFH）（rs1410996）和HTRA1（rs11200638）是否影响对兰尼单抗治疗方案的反应对于渗出的AMD。

著录项

期刊名称 International Journal of Ophthalmology
作者
Fernando Cruz-Gonzalez; Lucia Cabrillo-Estevez; Vanesa Rivero-Gutierrez; Ana Sanchez-Jara; Lourdes De Juan-Marcos; Rogelio Gonzalez-Sarmiento;
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作者单位

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年(卷),期 2016(9),9
年度 2016
页码 1304–1309
总页数 6
原文格式 PDF
正文语种
中图分类眼科学;
关键词
age-related macular degeneration polymorphisms ARMS2 HTRA1 complement factor H ranibizumab;

机译：年龄相关性黄斑变性;多态性;ARMS2;HTRA1;补体因子H;兰尼单抗;

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专利

1. Influence of CFH,HTRA1 and ARMS2 polymorphisms in the response to intravitreal ranibizumab treatment for wet age-related macular degeneration in a Spanish population [J] . Fernando Cruz-Gonzalez, Lucia Cabrillo-Estevez, Vanesa Rivero-Gutierrez, 国际眼科杂志：英文版 . 2016,第009期

机译：CFH，HTRA1和ARMS2多态性对玻璃体腔雷珠单抗治疗湿性年龄相关性黄斑变性的反应的影响
2. Influence of CFH,HTRA1 and ARMS2 polymorphisms in the response to intravitreal ranibizumab treatment for wet age-related macular degeneration in a Spanish population [J] . Fernando Cruz-Gonzalez, Lucia Cabrillo-Estevez, Vanesa Rivero-Gutierrez, 国际眼科杂志：英文版 . 2016,第009期

机译：CFH，HTRA1和ARMS2多态性对玻璃体腔雷珠单抗治疗湿性年龄相关性黄斑变性的反应的影响
3. CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration. [J] . McKibbin M, Ali M, Bansal S, British journal of ophthalmology . 2012,第2期

机译：CFH，VEGF和HTRA1启动子的基因型可能影响对新生血管性黄斑变性的玻璃体内兰尼单抗治疗的反应。
4. Expression Pattern of Kinin-Dependent Genes in Peripheral Blood Mononuclear Cells After Age-Related Macular Degeneration Treatment with Ranibizumab [C] . Michalska-Malecka K, Strzalka-Mrozik B., Kimsa M.W., International Symposium on Ocular Pharmacology and Therapeutics . 2013

机译：与RANIBIZIMAB的年龄相关黄斑治疗后外周血单核细胞在外周血单核细胞中的表达模式
5. Characterizing response patterns to ranibizumab therapy in patients with wet age-related macular degeneration: A latent class growth analysis [D] . Sun, Diana 2015

机译：潮湿年龄相关性黄斑变性患者的ranibizumab治疗的表征反应模式：潜在的增长分析
6. Joint Effect of CFH and ARMS2/HTRA1 Polymorphisms on Neovascular Age-Related Macular Degeneration in Chinese Population [O] . Kai Fang, Pei Gao, Jun Tian, 2015

机译：CFH和ARMS2 / HTRA1多态性对中国人群新血管性年龄黄斑变性的联合作用
7. Association between CFH, CFB, ARMS2, SERPINF1, VEGFR1 and VEGF polymorphisms and anatomical and functional response to ranibizumab treatment in neovascular age-related macular degeneration [O] . Estefania Cobos, Sergio Recalde, Jaouad Anter, 2017

机译：CFH，CFB，ARMS2，SerpinF1，VEGFR1和VEGF多态性与Ranibizumab治疗在新生血管时代相关性黄斑变性的解剖学和功能反应之间的关系

Influence of CFH HTRA1 and ARMS2 polymorphisms in the response to intravitreal ranibizumab treatment for wet age-related macular degeneration in a Spanish population

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