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Effect of green tea (camellia sinensis l.) leaf extract on reproductive system of adult male albino rats

机译:绿茶(山茶)叶提取物对成年雄性白化病大鼠生殖系统的影响

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摘要

Green tea leaf extract (GTLE), used in this experiment has shown great influence on male reproductive system functionally as well as morphologically. The extract was prepared according to the method of Wei. H. et al. The extract was given to two different experimental animal groups with two different doses during 26 consecutive days. After treatment it was found that, the weight of the testis was markedly reduced instead of normal weight gain of all the animals. The sperm count and motility were reduced for the treated groups as compared with control animal group. The enzymes like SGPT and SGOT were as usual and other blood parameters like glucose and protein were also as usual comparing with controlled group. Testosterone level was reduced in the treated groups. FSH and LH levels were also altered accordingly in treated groups. Histological examination showed inhibition of spermatogenesis as evidenced by disintegration of seminiferous tubules of testis. Result of this study showed that GTLE has potent castrative effect on male reproductive system in dose dependent manner.
机译:本实验中使用的绿茶叶提取物(GTLE)在功能和形态上均对雄性生殖系统产生很大影响。提取物是根据Wei的方法制备的。 H.等。在连续26天内,将提取物以两种不同的剂量分给两个不同的实验动物组。治疗后发现,所有动物的睾丸重量均显着降低,而不是正常的体重增加。与对照组相比,治疗组的精子数量和活力降低。与对照组相比,SGPT和SGOT等酶与往常一样,其他血液参数如葡萄糖和蛋白质也与往常一样。治疗组的睾丸激素水平降低。治疗组的FSH和LH水平也相应改变。组织学检查显示精子发生受到抑制,睾丸生精小管崩解证明了这一点。研究结果表明,GTLE对雄性生殖系统具有强效的剂量依赖性。

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