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Management of cervical ectopic pregnancy after unsuccesful methotrexate treatment

机译:甲氨蝶呤治疗失败后宫颈异位妊娠的处理

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摘要

>Background: Cervical pregnancy is rare and dangerous form of ectopic pregnancy which can be treated surgically or conservatively. Methotrexate is reasonable conservative option with high efficiency and acceptable level of side effects. Aim of this paper is to present possible treatment option in case of methotrexate failure, still keeping the postulates of minimal invasive surgery. >Case: We describe a case of cervical ectopic pregnancy in nulliparous female that was unsuccessfully treated with single dose, local, ultrasound guided intraamniotic methotrexate. Due to vaginal bleeding caused by remaining products of conception a hysteroscopic resection was performed. >Conclusion: Despite the problems that can occur in methotrexate treatment, it is still by far, cheapest and most effective treatment of cervical pregnancies. If necessary, procedure can be combined with other minimal invasive surgical procedures leading to satisfactory results. Hysteroscopic resection has enabled us to remove the product of conception from cervix making the minimal damage to the local tissue, thus preserving fertility.
机译:>背景:宫颈妊娠是异位妊娠的罕见和危险形式,可以通过手术或保守治疗。甲氨蝶呤是合理的保守选择,具有高效率和可接受的副作用水平。本文的目的是在甲氨蝶呤治疗失败的情况下提供可能的治疗选择,同时仍保留微创手术的原则。 >病例:我们描述了一个未生育女性宫颈异位妊娠的病例,该病例未接受单剂量,局部超声引导的羊膜内氨甲蝶呤治疗。由于剩余受孕产物引起的阴道出血,进行了宫腔镜切除术。 >结论:尽管甲氨蝶呤治疗可能会出现问题,但它仍然是迄今为止最便宜,最有效的宫颈妊娠治疗方法。如有必要,可将手术与其他微创外科手术相结合,从而获得满意的结果。宫腔镜切除术使我们能够从子宫颈中去除受孕产物,从而对局部组织的损害最小,从而保持了生育能力。

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