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A Custom-Developed Device for Testing Tensile Strength and Elasticity of Vascular and Intestinal Tissue Samples for Anastomosis Regeneration Research

机译:一种定制开发的设备用于测试血管和肠道组织样品的拉伸强度和弹性用于吻合再生研究

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摘要

Optimizing the regeneration process of surgically created anastomoses (blood vessels, intestines, nerves) is an important topic in surgical research. One of the most interesting parameter groups is related to the biomechanical properties of the anastomoses. Depending on the regeneration process and its influencing factors, tensile strength and other biomechanical features may change during the healing process. Related to the optimal specimen size, the range and accuracy of measurements, and applicability, we have developed a custom-tailored microcontroller-based device. In this paper, we describe the hardware and software configuration of the latest version of the device, including experiences and comparative measurements of tensile strength and elasticity of artificial materials and biopreparate tissue samples. The machine we developed was made up of easily obtainable parts and can be easily reproduced on a low budget. The basic device can apply a force of up to 40 newtons, and can grasp a 0.05–1 cm wide, 0.05–1 cm thick tissue. The length of the test piece on the rail should be between 0.3 and 5 cm. Low production cost, ease of use, and detailed data recording make it a useful tool for experimental surgical research.
机译:优化手术建立的吻合口(血管、肠道、神经)的再生过程是外科研究中的一个重要课题。最有趣的参数组之一与吻合口的生物力学特性有关。根据再生过程及其影响因素,拉伸强度和其他生物力学特征在愈合过程中可能会发生变化。根据最佳试样尺寸、测量范围和精度以及适用性,我们开发了一种定制的基于微控制器的设备。在本文中,我们描述了最新版本设备的硬件和软件配置,包括人造材料和生物制备组织样本的拉伸强度和弹性的经验和比较测量。我们开发的机器由容易获得的部件组成,可以在低预算下轻松复制。基本装置可以施加高达 40 牛顿的力,并且可以抓取 0.05-1 厘米宽、0.05-1 厘米厚的组织。导轨上试件的长度应在 0.3 到 5 厘米之间。生产成本低、易于使用和详细的数据记录使其成为实验外科研究的有用工具。

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