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Arthroplasty or internal fixation for displaced femoral neck fractures: which is the optimal alternative for elderly patients? A meta-analysis

机译:置换性股骨颈骨折的关节置换术或内固定术:哪种是老年患者的最佳选择?荟萃分析

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摘要

We conducted an up-to-date meta-analysis of 20 eligible randomised controlled trials (RCTs) containing 3,109 patients to compare arthroplasty with internal fixation of displaced femoral neck fractures regarding the effect on clinical outcomes. Computerised databases were searched for RCTs published from January 1979 to May 2008. The results showed that compared to internal fixation arthroplasty led to significantly fewer surgical complications at two and five years postoperatively and reduced the incidence of reoperation at one, two and five years postoperatively (P < 0.001). However, arthroplasty was associated with greater risk of deep wound infection, longer operating time and greater operative blood loss. Arthroplasty substantially increased the risk of reoperation following deep wound infection (P < 0.05). For mortality, there was increased postoperative risk for arthroplasty compared with internal fixation, but there was no statistically significant difference between the two groups at the different follow-up times. For pain at one year postoperatively, the result showed no statistically significant difference.Electronic supplementary materialThe online version of this article (doi:10.1007/s00264-009-0763-8) contains supplementary material, which is available to authorised users.
机译:我们对20项符合条件的随机对照试验(RCT)进行了最新的荟萃分析,其中包含3,109例患者,比较了置换术和股骨颈骨折内固定术对临床结局的影响。搜索计算机数据库以获取1979年1月至2008年5月发布的RCT。结果显示,与内固定关节置换术相比,术后2年和5年手术并发症明显减少,并减少了术后1年,2年和5年的再次手术发生率( P <0.001)。但是,人工关节置换术具有更大的深部伤口感染风险,更长的手术时间和更大的手术失血量。关节置换术大大增加了深部伤口感染后再次手术的风险(P <0.05)。对于死亡率,与内固定相比,术后置换的风险增加,但是两组在不同的随访时间没有统计学上的显着差异。对于术后一年的疼痛,结果无统计学差异。电子补充材料本文的在线版本(doi:10.1007 / s00264-009-0763-8)包含补充材料,授权用户可以使用。

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