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Mucosal acidification increases hydrogen sulfide release through up-regulating gene and protein expressions of cystathionine gamma-lyase in the rat gastric mucosa

机译：黏膜酸化通过上调大鼠胃黏膜中胱硫醚γ-裂解酶的基因和蛋白表达来增加硫化氢的释放

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摘要

Objective(s):This study was performed to investigate the effects of mucosal acidification on mRNA expression and protein synthesis of cystathionine gamma lyase (CSE), cystathionine beta synthase (CBS), and mucosal release of H2S in gastric mucosa in rats.

机译：目的：本研究旨在探讨粘膜酸化对大鼠胃粘膜中胱硫醚γ裂解酶（CSE），胱硫醚β合酶（CBS）的mRNA表达和蛋白质合成以及粘膜释放H2S的影响。

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期刊名称 Iranian Journal of Basic Medical Sciences
作者
Seyyed Ali Mard; Ali Veisi; Akram Ahangarpour; Mohammad Kazem Gharib-Naseri;
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作者单位

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年(卷),期 2016(19),2
年度 2016
页码 172–177
总页数 6
原文格式 PDF
正文语种
中图分类
关键词
Cystathionine gamma lyase H2S Mucosal acidification Rat;

机译：胱硫醚γ裂解酶H2S;粘膜酸化;大鼠;

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专利

1. Increased neointimal formation in cystathionine gamma-lyase deficient mice: Role of hydrogen sulfide in α5β1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells [J] . YangG., LiH., TangG., Journal of Molecular and Cellular Cardiology . 2012,第3期

机译：胱硫醚γ-裂解酶缺陷小鼠新内膜形成增加：硫化氢在平滑肌细胞中α5β1-整合素和基质金属蛋白酶-2表达中的作用
2. Gastric acid induces mucosal H2S release in rats by upregulating mRNA and protein expression of cystathionine gamma lyase [J] . Mard Seyyed Ali, Veisi Ali, Ahangarpour Akram, The journal of physiological sciences: JPS . 2015,第6期

机译：胃酸通过上调胱硫醚γ裂解酶的mRNA和蛋白表达诱导大鼠黏膜H2S释放
3. Gastric acid induces mucosal HSubscript2/SubscriptS release in rats by upregulating mRNA and protein expression of cystathionine gamma lyase [J] . Seyyed Ali Mard, Ali Veisi, Akram Ahangarpour, The journal of physiological sciences . 2015,第6期

机译：胃酸通过上调胱硫醚γ裂解酶的mRNA和蛋白表达诱导大鼠黏膜H 2 S释放
4. Expression of Gastric Mucosa Trefoil Factor Family 2 and Epidermal Growth Factor during Healing of Experimental Gastric Ulcer in Rats [C] . Zhang Jing, Wu Jing-fang, Fang Tao, Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on . 2012

机译：大鼠实验性胃溃疡愈合过程中胃粘膜三叶因子家族2和表皮生长因子的表达
5. Hydrogen sulfide biogenesis by and regulation of cystathionine beta-synthase. [D] . Singh, Sangita. 2009

机译：硫化氢的生物发生和胱硫醚β-合酶的调控。
6. Anti-Atherogenic Effect of Hydrogen Sulfide by Over-Expression of Cystathionine Gamma-Lyase (CSE) Gene [O] . Sau Ha Cheung, Wai Kei Kwok, Ka Fai To, -1

机译：半胱氨酸硫氨酸γ-裂解酶（CSE）基因过表达对硫化氢的抗动脉粥样硬化作用
7. Anti-atherogenic effect of hydrogen sulfide by over-expression of cystathionine gamma-lyase (CSE) gene. [O] . Sau Ha Cheung, Wai Kei Kwok, Ka Fai To, 2014

机译：通过胱硫醚γ-裂解酶（CsE）基因的过表达来实现硫化氢的抗动脉粥样硬化作用。

Mucosal acidification increases hydrogen sulfide release through up-regulating gene and protein expressions of cystathionine gamma-lyase in the rat gastric mucosa

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