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Symptom Management for Patients With Esophageal Cancer After Esophagectomy

机译:食管切除术后食管癌患者的症状管理

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摘要

>CASE STUDYKD is a 67-year-old man with a medical history of hypertension, asthma, and a 20-pack/year smoking history who developed progressive dysphagia 8 months ago. Upon consultation with his primary care provider, he underwent an esophagogastroduodenoscopy (EGD) for evaluation. A friable mass was visualized at the gastroesophageal junction, and biopsies confirmed adenocarcinoma of the esophagus. KD completed a staging evaluation with positron-emission tomography/computed tomography (PET/CT), which did not reveal distant metastatic disease. He also had an endoscopic ultrasound (EUS), which showed the tumor invading the muscularis propria and did not identify any enlarged regional lymph nodes (stage T3N0 disease).KD was referred to a medical oncologist and a radiation oncologist; he underwent concurrent chemoradiation therapy with docetaxel and fluorouracil and radiation therapy (50.4 Gy). KD was referred to thoracic surgery following restaging with PET/CT and EGD; there was no evidence of distant metastatic disease, and pathology findings revealed residual adenocarcinoma in one of the four esophageal biopsies.KD underwent Ivor Lewis esophagectomy and had a jejunostomy tube placed for nutritional requirements for 10 weeks as he adjusted to oral nutrition. Surgical pathology findings revealed residual adenocarcinoma with treatment effect; no malignancy was detected in the sampled regional lymph nodes.Four months later, KD presents with complaints of frequent postprandial diarrhea and reflux. He says he has been trying to lie down after meals due to palpitations and flushing. He is anxious about these symptoms and fearful about his long-term prognosis adjusting to the side effects of esophagectomy and would like to discuss lifestyle modifications.
机译:>案例研究:KD是一位67岁的男性,有高血压,哮喘病史,每年吸烟20包,8个月前发展为进行性吞咽困难。经咨询其初级保健提供者后,他接受了食管胃十二指肠镜(EGD)进行评估。在胃食管交界处观察到易碎的肿块,活检证实为食道腺癌。 KD用正电子发射断层扫描/计算机断层扫描(PET / CT)完成了分期评估,但未显示远处转移性疾病。他还接受了内镜超声检查(EUS),该超声检查显示肿瘤侵犯了固有肌层,并且未发现任何扩大的区域淋巴结(T3N0期疾病)。他同时接受了多西他赛和氟尿嘧啶的化学放射治疗以及放射治疗(50.4 Gy)。在用PET / CT和EGD分期后,将KD转到胸外科。没有证据表明有远处转移性疾病,病理结果显示在四例食管活检中有一例残留腺癌.KD接受了Ivor Lewis食管切除术,并经空肠造口管进行了10周的营养需要,因为他适应了口腔营养。手术病理结果显示残留腺癌具有治疗作用;在采样的区域淋巴结中未检测到恶性肿瘤。四个月后,KD出现餐后腹泻和反流频繁的主诉。他说,由于心pit和潮红,他一直试图在饭后躺下。他对这些症状感到焦虑,并担心适应食管切除术副作用的长期预后,并希望讨论生活方式的改变。

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