In device-aided therapy (DAT) for Parkinson’s disease (PD), factors such as device-related adverse effects, psychological and lifestyle changes, and specific disease progression can affect the quality of life (QoL) of patients with advanced PD. However, there is no existing QoL scale that includes the effects of therapeutic devices. From a semi-structured interview with patients with PD undergoing deep brain stimulation (DBS), we extracted the content of utterances that were thought to affect the QoL and created a draft questionnaire consisting of 113 items. This questionnaire was administered to 54 other patients undergoing DBS, whose data were examined for reliability and validity by factor analysis, and finally, a 24-item PD QoL questionnaire for patients on DAT (PDQ-DAT) was developed. Presently, the PDQ-DAT is the only scale that can assess the QoL of patients on DAT, including the influence treatment devices have on them. In the future, it might be used to help in shared decision-making in medicine by incorporating the patient’s sense of burden and values in the selection of treatment methods.
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机译：在帕金森病 （PD） 的设备辅助疗法 （DAT） 中，与设备相关的不良反应、心理和生活方式变化以及特定疾病进展等因素会影响晚期 PD 患者的生活质量 （QoL）。然而，没有现有的 QoL 量表包括治疗设备的效果。从对接受深部脑刺激 （DBS） 的 PD 患者的半结构化访谈中，我们提取了被认为会影响 QoL 的话语内容，并创建了一份包含 113 个项目的问卷草案。该问卷对其他 54 名接受 DBS 的患者进行调查，通过因子分析检查其数据的信度和效度，最后，为 DAT 患者 （PDQ-DAT） 开发了一份包含 24 个项目的 PD QoL 问卷。目前，PDQ-DAT 是唯一可以评估患者接受 DAT 的 QoL 的量表，包括治疗设备对他们的影响。将来，它可能通过将患者的负担感和价值观纳入治疗方法的选择来帮助医学中的共同决策。
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