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Early Detection and Intervention for Hirschsprung’s Disease: A Key to Successful Outcomes

机译:先天性巨结肠的早期发现和干预:成功的关键

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摘要

Hirschsprung’s disease is a congenital disorder characterized by the absence of nerve cells in the colon muscles, leading to difficulties in evacuating stool. This case report describes a newborn patient presenting with typical symptoms of the disease, including abdominal distension, constipation, diarrhea, and fever. The patient’s initial laboratory investigations revealed anemia (Hb: 9.80 g/dL), low RBC count (3.50 million/cu mm), elevated RDW (16.70%), increased WBC count (11 000/cu mm), and raised platelet levels (891 000/µL) along with an elevated CRP (3.22). The baby received a comprehensive treatment regimen, including blood transfusion, Syp. MVBC, Enterogermina, Inj. Pan, Inj. Metro, Inj. Piptaz, Inj. Vancomycin, Calcium gluconate, and Inj. Aminoven. Following this treatment and necessary surgical intervention, the patient demonstrated significant improvement in frequent bowel movements and alleviation of other symptoms. This case highlights the importance of prompt diagnosis and multidisciplinary management for favorable outcomes in infants with Hirschsprung’s disease.
机译:先天性巨结肠是一种先天性疾病,其特征是结肠肌肉中没有神经细胞,导致排便困难。本病例报告描述了一名新生儿患者,表现为该病的典型症状,包括腹胀、便秘、腹泻和发热。患者的初步实验室检查显示贫血 (Hb: 9.80 g/dL)、低红细胞计数 (350 万/立方毫米 )、RDW 升高 (16.70%)、白细胞计数增加 (11 000/立方毫米 )和血小板水平升高 (891 000/μL) 以及 CRP 升高 (3.22)。婴儿接受了全面的治疗方案,包括输血、Syp.MVBC、Enterogermina、Inj. Pan、Inj. Metro、Inj. Piptaz、Inj. Vancomycin、葡萄糖酸钙和 Inj. Aminoven。在这种治疗和必要的手术干预之后,患者在频繁排便和其他症状方面表现出显着改善。该病例强调了及时诊断和多学科管理对先天性巨结肠婴儿良好结局的重要性。

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